@Article{信息:doi 10.2196 / / jmir。1756年，作者=“Neve, Melinda and Morgan, Philip J and Collins, Clare E”，标题=“基于web的商业减肥计划的体重变化及其与网站使用的关联:队列研究”，期刊=“J Med Internet Res”，年=“2011”，月=“10月”，日=“12”，卷=“13”，数=“4”，页=“e83”，关键词=“减肥;肥胖;干预;互联网;背景:科学文献中缺乏关于商业减肥计划有效性的信息，包括基于网络的减肥计划。基于网络的减肥计划的潜力已经得到承认，但它们实现显著减肥的能力尚未得到证实。目的:目的是评估参加基于网络的商业减肥计划12周或52周的大型人群的体重变化，并描述参与者使用该计划与体重变化的关系。方法:从2007年8月15日到2008年5月31日，参与者参加了澳大利亚一个基于网络的商业减肥计划。使用自我报告的每周体重记录来确定12周和52周后的体重变化。 The primary analysis estimated weight change using generalized linear mixed models (GLMMs) for all participants who subscribed for 12 weeks and also for those who subscribed for 52 weeks. A sensitivity analysis was conducted using the last observation carried forward (LOCF) method. Website use (ie, the number of days participants logged on, made food or exercise entries to the Web-based diary, or posted to the discussion forum) was described from program enrollment to 12 and 52 weeks, and differences in website use by percentage weight change category were tested using Kruskal-Wallis test for equality of populations. Results: Participants (n = 9599) had a mean (standard deviation [SD]) age of 35.7 (9.5) years and were predominantly female (86{\%} or 8279/9599) and obese (61{\%} or 5866/9599). Results from the primary GLMM analysis including all enrollees found the mean percentage weight change was −6.2{\%} among 12-week subscribers (n = 6943) and −6.9{\%} among 52-week subscribers (n = 2656). Sensitivity analysis using LOCF revealed an average weight change of −3.0{\%} and −3.5{\%} after 12 and 52 weeks respectively. The use of all website features increased significantly (P < .01) as percentage weight change improved. Conclusions: The weight loss achieved by 12- and 52-week subscribers of a commercial Web-based weight loss program is likely to be in the range of the primary and sensitivity analysis results. While this suggests that, on average, clinically important weight loss may be achieved, further research is required to evaluate the efficacy of this commercial Web-based weight loss program prospectively using objective measures. The potential association between greater website use and increased weight loss also requires further evaluation, as strategies to improve participants' use of Web-based program features may be required. ", issn="1438-8871", doi="10.2196/jmir.1756", url="//www.mybigtv.com/2011/4/e83/", url="https://doi.org/10.2196/jmir.1756", url="http://www.ncbi.nlm.nih.gov/pubmed/21993231" }