@Article{信息:doi 10.2196 / / jmir。1370年，作者=“Mohr, David C和Duffecy, Jennifer和Jin, Ling和Ludman, Evette J和Lewis, Adam和Begale, Mark和McCarthy Jr, Martin”，标题=“抑郁症的多模式电子心理健康治疗:一个可行性试验”，期刊=“J医学互联网研究”，年=“2010”，月=“12”，日=“19”，卷=“12”，数=“5”，页=“e48”，关键词=“抑郁症;互联网;可行性;电话;背景:互联网干预对抑郁症的依从性并不理想。本研究描述了一种多模态电子心理健康干预的可行性试验，旨在提高抑郁症的依从性和预后。干预需要频繁的简短登录自我监测和反馈，以及在理论驱动的手册协议指导下的电子邮件和简短电话支持。目的:本可行性试验的目的是检查我们的互联网干预加上人工电话支持项目是否会导致提高坚持率和改善抑郁结果。方法:这是一项为期7周的单臂可行性试验。 Results: Of the 21 patients enrolled, 2 (9.5{\%}) dropped out of treatment. Patients logged in 23.2 {\textpm} 12.2 times over the 7 weeks. Significant reductions in depression were found on all measures, including the Patient Health Questionnaire depression scale (PHQ-8) (Cohen's d = 1.96, P < .001), the Hamilton Rating Scale for Depression (d = 1.34, P < .001), and diagnosis of major depressive episode (P < .001). Conclusions: The attrition rate was far lower than seen either in Internet studies or trials of face-to-face interventions, and depression outcomes were substantial. These findings support the feasibility of providing a multimodal e-mental health treatment to patients with depression. Although it is premature to make any firm conclusions based on these data, they do support the initiation of a randomized controlled trial examining the independent and joint effects of Internet and telephone administered treatments for depression. ", issn="1438-8871", doi="10.2196/jmir.1370", url="//www.mybigtv.com/2010/5/e48/", url="https://doi.org/10.2196/jmir.1370", url="http://www.ncbi.nlm.nih.gov/pubmed/21169164" }