TY - JOUR AU - Ateudjieu, Jérôme AU - Tchio-Nighie, Ketina Hirma AU - Goura, André Pascal AU - Ndinakie, Martin Yakum AU - Dieffi Tchifou, Miltiade AU - Amada, Lapia AU - Tsafack, Marcelin AU - Kiadjieu Dieumo, Frank Forex AU - Guenou, Etienne AU - Nangue, Charlette AU - Kenfack, Bruno PY - 2022 DA - 2022/3/1 TI -跟踪人口流动和免疫状况以改善儿童获得免疫接种:基于实地的随机对照试验JO - JMIR公共卫生监测SP - e32213 VL - 8 IS - 3kw -免疫状况KW -覆盖率KW -完整性KW -及时性KW -扩大免疫计划疫苗KW -五岁以下儿童KW - Foumban KW -喀麦隆KW -移动电话AB -背景:各国扩大免疫规划(EPI)有助于降低死亡率和发病率，但在大多数低收入国家，获得这些疫苗的机会仍然有限。目的:我们旨在评估让社区志愿者(CVs)跟踪儿童的疫苗接种状况和人口流动，并使用记录数据来规划追赶免疫会议，是否可以提高儿童疫苗接种的及时性、完整性和覆盖率。方法:这是一项基于实地的随机对照试验，喀麦隆西部Foumban卫生区的社区被分配为干预组或对照组。在干预组中，每个社区都有一名CV接受培训，在一年内每月访问家庭，评估并在登记册中记录计划免疫目标儿童的详细信息、他们的人口流动和免疫状况。扫描的记录页面通过WhatsApp发送给卫生中心免疫小组，并用于组织每月的社区免疫补补会议。在对照组，计划免疫接种疗程是常规进行的。两个研究组分别在干预开始后6个月和12个月进行调查，以评估和比较免疫及时性、覆盖率和完整性。结果:总体而言，在中线和终点，每个集群调查了30栋建筑。在干预组中线和终点的633个和729个访问家庭中，分别有630个(99.5%)和718个(98.4%)同意参与。 In the control group, 507 and 651 households were visited and 505 (99.6%) and 636 (97.7%), respectively, consented to participate. At 12 months intervention, the month one timeliness of bacille Calmette–Guerin (BCG) vaccine did not increase in the intervention group compared with the control group for the age groups 0-11 months (adjusted odds ratio [aOR] 1.1, 95% CI 0.7-1.8) and 0-59 months (aOR 1.1, 95% CI 0.9-1.4), and significantly increased for the first-year BCG vaccine administration for the age group 0-23 months (aOR 1.5, 95% CI 1.1-2.2). The coverage of diphtheria-pertussis-tetanus and hepatitis B+Hemophilus influenzae type B (DPT-Hi +Hb) dose 3 (aOR 2.0, 95% CI 1.5-2.7) and of DPT-Hi+Hb dose 1 (aOR 1.8, 95% CI 1.4-2.4) vaccines increased significantly in the intervention group compared with the control group in the age groups 12-59 months and 12-23 months, respectively. Specific (DPT-Hi+Hb dose 1 to DPT-Hi+Hb dose 3: aOR 1.9, 95% CI 1.4-2.6) and general (BCG to measles: aOR 1.5, 95% CI 1.1-2.1) vaccine completeness increased significantly in the intervention group compared with the control group. Conclusions: Findings support that involving CVs to track children’s vaccination status and demographic movements and using recorded data to plan catch-up immunization sessions improve children’s vaccination timeliness, completeness, and coverage. This strategy should be adopted to improve access to vaccination for EPI target populations and the consistency verified in other contexts. Trial Registration: Pan African Clinical Trials Registry PACTR201808527428720; https://pactr.samrc.ac.za/TrialDisplay.aspx?TrialID=3548 SN - 2369-2960 UR - https://publichealth.www.mybigtv.com/2022/3/e32213 UR - https://doi.org/10.2196/32213 UR - http://www.ncbi.nlm.nih.gov/pubmed/35230249 DO - 10.2196/32213 ID - info:doi/10.2196/32213 ER -