用后退组微米波快速抗原检测大规模筛查SARS-CoV-2的研究卡塔尔世界杯8强波胆分析香港中文大学新发传染病研究中心,香港沙田威尔斯亲王医院研究生教育中心207室,电话:852 22528862,sslee@cuhk.edu.hk %K COVID-19 %K SARS-CoV-2抗原检测%K COVID-19疫苗%K大规模筛查%K抗原检测%K流行病学%K Omicron %K香港%K公共卫生%K爆发%K流行%K筛查%K传播%K在线%K疫苗接种%K疫苗%K监测%D 2022 %7 9.11.2022 %9 JMIR公共卫生监测%G英文%X背景:香港的COVID-19 Omicron BA.2流行波在2022年第一季度达到顶峰。在实施严格的公共卫生措施后,每天报告的病例数从5万多例下降到2000例以下。尽管疫情稳步消退,但政府开展了为期3天的“自愿普遍快速检测”活动,邀请所有公民每天自行进行快速抗原检测,以识别未被发现的流行感染。目的:评价鼠群筛查的接受情况和结果,以估计人群的残留疫情负担,评估进一步传播的风险。方法:在RAT活动一周后进行了一项包括开放式网络人口调查的横断面研究。参与者被要求报告他们在此期间的COVID-19疫苗接种和感染史以及RAT表现和检测结果。他们还被邀请报告他们共同生活的个体的测试表现和结果。询问了不接受的原因。 Testing and positive rates were age-adjusted. Determinants of undergoing RAT were identified using univariable and multivariable logistic regression models. Results: In total, particulars from 21,769 individuals were reported by 8338 participants. The overall age-adjusted testing rate was 74.94% (95% CI 73.71%-76.18%), with over 80% of participants in the age groups between 45-84 years having self-performed RAT during the campaign period. After age-adjustment, 1.03% (95% CI 0.86%-1.21%) of participants tested positive. The positive rates in the age groups between 20-29 years and >84 years exceeded 2%. Taking into account the positive rate and 5819 reported cases during the period, the cases identified in the campaign might account for 7.65% (95% CI 6.47%-9.14%) of all infections. Testers were more likely to be female, older, not previously diagnosed with COVID-19, and have received COVID-19 vaccination. Adjusting for the number of household members, those living with a child aged <12 years and whose household members were also tested were more likely to have self-performed an RAT. Main reasons for not performing an RAT included the absence of symptoms (598/1108, 53.97%), disbelief of the appropriateness of the campaign as an antiepidemic measure (355/1108, 32.04%), and a recent COVID-19 diagnosis (332/1108, 29.96%). Conclusions: The residual population burden remained substantial in spite of the clear evidence of a receding epidemic wave. Despite caution in generalization to the Hong Kong population, the high participation rate in mass screening indicated that the voluntary RAT was well accepted, making it a feasible option for implementation as a complementary means of public health surveillance. %M 36240027 %R 10.2196/40175 %U https://publichealth.www.mybigtv.com/2022/11/e40175 %U https://doi.org/10.2196/40175 %U http://www.ncbi.nlm.nih.gov/pubmed/36240027
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