杂志文章%@ 2369- 2960% I JMIR出版物%V 8% N卡塔尔世界杯8强波胆分析 10% P e37790% T对乙酰氨基酚在骨关节炎和腰痛患者中的应用:电子病历数据的信息流行病学研究和观察分析%A Pickering,Gisèle %A Mezouar,Linda %A Kechemir,Hayet %A Ebel-Bitoun,Caty + Clinique调查中心，Inserm 1405, CHU Clermont-Ferrand, Rue Montalembert, CHU G Montpied, Clermont-Ferrand, 63000，法国，33 473178416，gisele.pickering@uca.fr %K骨关节炎%K腰痛%K全科医生%K风湿病%K对乙酰氨酚%K真实证据%D 2022 %7 27.10.2022 %9原始论文%J JMIR公共卫生监测%G英文%X背景:腰痛(LBP)和骨关节炎(OA)是常见的肌肉骨骼疾病，占全球残疾寿命的17.0%左右;然而，缺乏关于这些情况的真实数据。在法国，对乙酰氨基酚品牌经常被用于肌肉骨骼疼痛，包括Doliprane, Dafalgan和Ixprim(曲马多-对乙酰氨基酚)。目的:本回顾性研究的目的是了解LBP或OA患者在使用对乙酰氨基酚治疗时的旅程。方法:进行三项研究。两项研究分析了2013年至2018年期间在法国至少接受过一次扑热息痛处方的OA或LBP患者的全科医生(gp)和风湿病医生的电子医疗记录。数据被提取、匿名，并按性别、年龄和提供者专业进行分层。第三项研究是一项信息流行病学研究，分析了法国和美国的公共医疗论坛和Twitter上使用的术语之间的关联，仅针对OA。 Results: In the first 2 studies, among patients with LBP (98,998), most (n=92,068, 93.0%) saw a GP, and Doliprane was a first-line therapy for 87.0% (n=86,128) of patients (71.0% [n=61,151] in combination with nonsteroidal anti-inflammatory drugs [NSAIDs] or opioids). Among patients with OA (99,997), most (n=84,997, 85.0%) saw a GP, and Doliprane was a first-line therapy for 83.0% (n=82,998) of patients (62.0% [n=51,459] in combination). Overall, paracetamol monotherapy prescriptions decreased as episodes increased. In the third study, in line with available literature, the data confirmed that the prevalence of OA increases with age (91.5% [212,875/232,650] above 41 years), OA is more predominant in females (46,530/232,650, 20.0%), and paracetamol use varies between GPs and rheumatologists. Conclusions: This health surveillance analysis provides a better understanding of the journey for patients with LBP or OA. These data confirmed that although paracetamol remains the most common first-line analgesic for patients with LBP and OA, usage varies among patients and health care specialists, and there are concerns over efficacy. %M 363015 %R 10.2196/37790 %U https://publichealth.www.mybigtv.com/2022/10/e37790 %U https://doi.org/10.2196/37790 %U http://www.ncbi.nlm.nih.gov/pubmed/363015