美国胃肠道症状搜索查询兴趣与COVID-19诊断的关联:卡塔尔世界杯8强波胆分析信息流行病学研究%A Rajan,Anjana Sharaf,Ravi %A Brown,Robert S %A Sharaiha,Reem Z %A Lebwohl,Benjamin %A Mahadev,SriHari %+美国纽约纽约大街1305号4楼威尔康奈尔医学院消化内科和肝脏内科，纽约州，10065，美国，1 646 962 2382srm9005@med.cornell.edu %K COVID-19 %K腹泻%K互联网搜索查询%K谷歌趋势%K胃肠道%K症状%K健康信息%K大流行%K传染病%K病毒%D 2020 %7 17.7.2020 %9短论文JMIR公共卫生监测%G英语%X背景:冠状病毒病(COVID-19)是一种在世界范围内迅速传播的新型病毒性疾病。虽然该疾病主要表现为呼吸道疾病，但在多达三分之一的确诊病例中报告了腹泻等胃肠道症状，患者可能有轻微症状，这并不促使他们寻求医疗照顾。基于互联网的信息流行病学提供了一种在人群水平上研究症状的方法，即使是在不寻求医疗保健的个人中。目的:本研究旨在确定美国胃肠道症状的互联网搜索量与COVID-19确诊病例数之间是否存在相关性。方法:在本研究中选择用于分析的搜索词包括常见的胃肠道症状，如腹泻、恶心、呕吐和腹痛。此外，搜索词发烧和咳嗽被用作阳性对照，便秘被用作阴性对照。在2019年10月1日至2020年6月15日期间，从谷歌趋势中获得了美国所有州对选定症状的每日查询份额。这些份额分为两个时间段:covid -19前(3月1日之前)和covid -19后(3月1日至6月15日)。 Confirmed COVID-19 case numbers were obtained from the Johns Hopkins University Center for Systems Science and Engineering data repository. Moving averages of the daily query shares (normalized to baseline pre–COVID-19) were then analyzed against the confirmed disease case count and daily new cases to establish a temporal relationship. Results: The relative search query shares of many symptoms, including nausea, vomiting, abdominal pain, and constipation, remained near or below baseline throughout the time period studied; however, there were notable increases in searches for the positive control symptoms of fever and cough as well as for diarrhea. These increases in daily search queries for fever, cough, and diarrhea preceded the rapid rise in number of cases by approximately 10 to 14 days. The search volumes for these terms began declining after mid-March despite the continued rises in cumulative cases and daily new case counts. Conclusions: Google searches for symptoms may precede the actual rises in cases and hospitalizations during pandemics. During the current COVID-19 pandemic, this study demonstrates that internet search queries for fever, cough, and diarrhea increased prior to the increased confirmed case count by available testing during the early weeks of the pandemic in the United States. While the search volumes eventually decreased significantly as the number of cases continued to rise, internet query search data may still be a useful tool at a population level to identify areas of active disease transmission at the cusp of new outbreaks. %M 32640418 %R 10.2196/19354 %U http://publichealth.www.mybigtv.com/2020/3/e19354/ %U https://doi.org/10.2196/19354 %U http://www.ncbi.nlm.nih.gov/pubmed/32640418