在线对话监测以了解阿片类药物的流行;卡塔尔世界杯8强波胆分析流行病学监测研究%A Black,Joshua C . A Margolin,Zachary R . A Olson,Richard A . A Dart,Richard C . + Rocky Mountain Poison and Drug Safety, 1391 N Speer Blvd #600, M/C 0180，美国科罗拉多州丹佛市，80204,1 303 389 1652，joshua.black@rmpds.org %K流行病学监测%K信息监测%K信息流行病学%K阿片类药物%K社交媒体%K滥用%K成瘾%K过量%K死亡%D 2020 %7 29.6.2020 %9 JMIR公共卫生监测%G英文%X背景:2016 - 2017年，全国阿片类药物死亡率持续上升;阿片类药物死亡人数从42,249人增加到47,600人，使公共卫生危机达到新的高度。考虑到美国69%的成年人使用在线社交媒体网站，建立对处方药误用和滥用的更全面了解的资源可以补充传统的监测工具。美国食品和药物管理局已经确定了阿片类药物的五大风险和后果——误用、滥用、成瘾、过量和死亡。识别讨论这些关键风险的帖子可能会带来传统监测系统通常无法捕捉到的新信息。目的:本研究的目的是描述美国涉及滥用、误用、成瘾、过量和死亡的在线帖子的趋势(频率随时间的变化)，并描述主持这些讨论的网站类型。研究人员检查了互联网上提到芬太尼、氢可酮、羟考酮或羟吗啡酮的帖子。方法:删除不涉及个人经历的帖子，保留310万条帖子。 A stratified sample of 61,000 was selected. Unstructured data were classified into 5 key risks by manually coding for key outcomes of misuse, abuse, addiction, overdose, and death. Sampling probabilities of the coded posts were used to estimate the total post volume for each key risk. Results: Addiction and misuse were the two most commonly discussed key risks for hydrocodone, oxycodone, and oxymorphone. For fentanyl, overdose and death were the most discussed key risks. Fentanyl had the highest estimated number of misuse-, overdose-, and death-related mentions (41,808, 42,659, and 94,169, respectively). Oxycodone had the highest estimated number of abuse- and addiction-related mentions (3548 and 12,679, respectively). The estimated volume of online posts for fentanyl increased by more than 10-fold in late 2017 and 2018. The odds of discussing fentanyl overdose (odds ratios [OR] 4.32, 95% CI 2.43-7.66) and death (OR 5.05, 95% CI 3.10-8.21) were higher for social media, while the odds of discussing fentanyl abuse (OR 0.10, 95% CI 0.04-0.22) and addiction (OR 0.24, 95% CI 0.15-0.38) were higher for blogs and forums. Conclusions: Of the 5 FDA-defined key risks, fentanyl overdose and death has dominated discussion in recent years, while discussion of oxycodone, hydrocodone, and oxymorphone has decreased. As drug-related deaths continue to increase, an understanding of the motivations, circumstances, and consequences of drug abuse would assist in developing policy responses. Furthermore, content was notably different based on media origin, and studies that exclusively use either social media sites (such as Twitter) or blogs and forums could miss important content. This study sets out sustainable, ongoing methodology for surveilling internet postings regarding these drugs. %M 32597786 %R 10.2196/17073 %U http://publichealth.www.mybigtv.com/2020/2/e17073/ %U https://doi.org/10.2196/17073 %U http://www.ncbi.nlm.nih.gov/pubmed/32597786