@文章{信息:doi/10.2196/20913，作者="Saposnik, Florencia E and Huber, Joelene F"，标题="过去15年自闭症病因和治疗的网络搜索趋势:探索性信息流行病学研究"，期刊="JMIR儿科家长"，年="2020"，月=" 12月"，日="7"，卷="3"，数="2"，页数="e20913"，关键词="自闭症;infodemiology;infoveillance;信息学;背景:90%的美国成年人使用互联网，大多数互联网用户报告使用搜索引擎在网上搜索健康信息。自闭症谱系障碍(ASD)的发病率不断上升，其病因的不确定性以及各种干预方法都导致了关于其原因和治疗的问题。目前尚不清楚人们最常搜索有关ASD的哪些术语，也不知道网络搜索查询是否随着时间的推移而发生了变化。信息流行病学是一个健康信息学研究领域，使用大数据分析来理解网络搜索行为。目的:目的是:(1)使用信息流行病学数据分析基于网络的关于ASD原因和治疗方法的搜索趋势;(2)告知临床医生和ASD组织关于ASD的网络查询。方法:使用谷歌Trends分析2004年至2019年美国有关ASD原因和治疗的网络搜索。 The search terms analyzed for queries about causes of ASD included vaccines, genetics, environmental factors, and microbiome and those for therapies included applied behavior analysis (ABA), gluten-free diet, chelation therapy, marijuana, probiotics, and stem cell therapy. Results: Google Trends results are normalized on a scale ranging from 0 to 100 to represent the frequency and relative interest of search topics. For searches about ASD causes, vaccines had the greatest frequency compared to other terms, with an initial search peak observed in 2008 (scaled score of 81), reaching the highest frequency in 2015 (scaled score of 100), and a current upward trend. In comparison, searches about genetics, environmental factors, and microbiome occurred less frequently. For web searches about ASD therapies, ABA consistently had a high frequency of search interest since 2004, reaching a maximum scaled score of 100 in 2019. The analyses of chelation therapy and gluten-free diet showed trending interest in 2005 (scaled score of 68) and 2007 (scaled score of 100), respectively, followed by a steady decline since (scaled scores of only 10 and 16, respectively, in 2019). Searches related to ASD and marijuana showed a rise in 2009 (scaled score of 35), and they continue to trend upward. Searches about probiotics and stem cell therapy have been relatively low (scaled scores of 22 and 18, respectively), but are gradually gaining interest. Web search volumes for stem cell therapy in 2019 surpassed both gluten-free diet and chelation therapy as web-searched interventions for ASD. Conclusions: Google Trends is an effective infodemiology tool to analyze large-scale web search trends about ASD. The results showed informative variation in search trends over 15 years. These data are useful to inform clinicians and organizations about web queries on topics related to ASD, identify knowledge gaps, and target web-based education and knowledge translation strategies. ", issn="2561-6722", doi="10.2196/20913", url="http://pediatrics.www.mybigtv.com/2020/2/e20913/", url="https://doi.org/10.2196/20913", url="http://www.ncbi.nlm.nih.gov/pubmed/33284128" }