TY - JOUR AU - Domogalla, Lena AU - Beck, Alena AU - Schulze-Hagen, Theresa AU - Herr, Raphael AU - Benecke, Johannes AU - Schmieder, Astrid PY - 2021 DA - 2021/10/25 TI -电子健康智能手机应用程序对牛皮癣患者心理健康的影响:前瞻性随机对照干预研究JO - JMIR Mhealth Uhealth SP - e28149 VL - 9 IS - 10 KW -牛皮癣KW -电子健康KW -移动健康KW -远程医疗KW -远程皮肤科KW -患者教育计划KW -疾病管理KW -智能手机应用KW -心理健康KW -手机AB -背景:牛皮癣对患者身心健康有负面影响，可导致焦虑和抑郁。疾病管理策略，包括教育计划和电子健康设备，已被证明可以改善几种慢性疾病的卫生保健。然而，在牛皮癣患者的日常护理中缺乏这种疾病管理策略。目的:本研究旨在研究将教育计划与疾病管理智能手机应用程序相结合的新型干预措施对牛皮癣患者心理健康的影响。方法:干预组银屑病患者接受教育;在第0、12、24、36和60周就诊;并且可以访问学习应用程序。对照组的患者只参加访问。主要终点是医院焦虑和抑郁量表(HADS)得分的显著降低。次要终点是皮肤病学生活质量指数评分、牛皮癣面积和严重程度指数评分、瘙痒和疼痛的减少，以及情绪和日常活动的改善。 In addition, modulating effects of sex, age, disease duration, and app use frequency were evaluated. Results: A total of 107 patients were included in the study and randomized into the control group (53/107, 49.5%) or intervention group (54/107, 50.5%). Approximately 71.9% (77/107) of the patients completed the study. A significant reduction in HADS-Depression (HADS-D) in the intervention group was found at weeks 12 (P=.04) and 24 (P=.005) but not at weeks 36 (P=.12) and 60 (P=.32). Patient stratification according to app use frequency showed a significant improvement in HADS-D score at weeks 36 (P=.004) and 60 (P=.04) and in HADS-Anxiety (HADS-A) score at weeks 36 (P=.04) and 60 (P=.05) in the group using the app less than once every 5 weeks. However, in patients using the app more than once every 5 weeks, no significant reduction in HADS-D (P=.84) or HADS-A (P=.20) score was observed over the 60-week study period compared with that observed in patients in the control group. All findings were independent of sex, age, and disease duration. Conclusions: These findings support the use of a disease management smartphone app as a valid tool to achieve long-term improvement in the mental health of patients with psoriasis if it is not used too frequently. Further studies are needed to analyze the newly observed influence of app use frequency. Trial Registration: Deutsches Register Klinischer Studien DRKS00020755; https://tinyurl.com/nyzjyvvk SN - 2291-5222 UR - https://mhealth.www.mybigtv.com/2021/10/e28149 UR - https://doi.org/10.2196/28149 UR - http://www.ncbi.nlm.nih.gov/pubmed/34431478 DO - 10.2196/28149 ID - info:doi/10.2196/28149 ER -