TY -的AU -格雷厄姆,莎拉·安妮AU -杰斯特,Dilip V AU -李,艾伦·E盟——吴Tsung-Chin盟——你,鑫盟——金正日Ho-Cheol AU -德普,科林PY - 2019 DA - 2019/10/23 TI -心率变异性与戴传感器测量之间的关联和老年人的生理功能:观察研究乔- JMIR Mhealth Uhealth SP - e13757六世- 7 - 10 KW -可穿戴技术千瓦老化KW -心电图KW -老年评估AB -背景:心率变异性(HRV)，或心跳间隔的变化，是心血管系统自主调节的量化指标。据报道，来自心电图(ECG)记录的低HRV与老年人的身体虚弱有关。可穿戴技术的最新进展为更容易地将HRV监测集成到定期的临床老年健康评估中提供了机会。然而，从心电和可穿戴式光体积描记术(PPG)设备获得的信号是不同的，在它们广泛使用之前，关键的第一步是确定从PPG设备获得的HRV指标是否也与老年人的身体功能有关。目的:本研究旨在调查手腕式PPG设备Empatica E4传感器测量的HRV与在持续护理老年住房社区独立生活的老年人队列中验证客观和自我报告的身体功能的临床测量之间的关系。我们的主要假设是，较低的HRV与较低的身体功能有关。此外，我们预计HRV将解释身体健康状况测量中显著比例的差异。方法:我们评估了77名参与者，他们来自一项持续研究，年龄在65到95岁之间的老年人。评估包括对通常列入老年健康评估的领域的彻底审查。 We collected HRV data with the Empatica E4 device and examined bivariate correlations between HRV quantified with the triangular index (HRV TI) and 3 widely used and validated measures of physical functioning—the Short Physical Performance Battery (SPPB), Timed Up and Go (TUG), and Medical Outcomes Study Short Form 36 (SF-36) physical composite scores. We further investigated the additional predictive power of HRV TI on physical health status, as characterized by SF-36 physical composite scores and Cumulative Illness Rating Scale for Geriatrics (CIRS-G) scores, using generalized estimating equation regression analyses with backward elimination. Results: We observed significant associations of HRV TI with SPPB (n=52; Spearman ρ=0.41; P=.003), TUG (n=51; ρ=−0.40; P=.004), SF-36 physical composite scores (n=49; ρ=0.37; P=.009), and CIRS-G scores (n=52, ρ=−0.43; P=.001). In addition, the HRV TI explained a significant proportion of variance in SF-36 physical composite scores (R2=0.28 vs 0.11 without HRV) and CIRS-G scores (R2=0.33 vs 0.17 without HRV). Conclusions: The HRV TI measured with a relatively novel wrist-worn PPG device was related to both objective (SPPB and TUG) and self-reported (SF-36 physical composite) measures of physical function. In addition, the HRV TI explained additional variance in self-reported physical function and cumulative illness severity beyond traditionally measured aspects of physical health. Future steps include longitudinal tracking of changes in both HRV and physical function, which will add important insights regarding the predictive value of HRV as a biomarker of physical health in older adults. SN - 2291-5222 UR - http://mhealth.www.mybigtv.com/2019/10/e13757/ UR - https://doi.org/10.2196/13757 UR - http://www.ncbi.nlm.nih.gov/pubmed/31647469 DO - 10.2196/13757 ID - info:doi/10.2196/13757 ER -