%0期刊文章%@ 2291-5222 %I JMIR出版物%V 9% 卡塔尔世界杯8强波胆分析N 10% P e28149% T电子健康智能手机应用程序对银屑病患者心理健康的影响:前瞻性随机对照干预研究%A Domogalla,Lena %A Beck,Alena %A Schulze-Hagen,Theresa %A Herr,Raphael %A Benecke,Johannes %A Schmieder,Astrid %+大学医院皮肤科Würzburg, Josef-Schneider-Straße 2, Haus D8, Würzburg，德国，49 931 201 26235，astrid.schmieder@umm.de %K银屑病%K eHealth %K mHealth %K远程医疗%K远程皮肤科%K患者教育计划%K疾病管理%K智能手机应用%K心理健康%K手机%D 2021 %7 25.10.2021 %9原始论文%J JMIR mHealth Uhealth %G英文%X背景:银屑病对患者的身心健康有负面影响，可导致焦虑和抑郁。疾病管理策略，包括教育计划和电子医疗设备，已被证明可以改善几种慢性疾病的医疗保健。然而，这种疾病管理策略在银屑病患者的日常护理中缺乏。目的:本研究旨在研究一种将教育计划与疾病管理智能手机应用程序相结合的新型干预措施对银屑病患者心理健康的影响。方法:干预组银屑病患者接受教育教育;在第0、12、24、36和60周进行随访;并且可以使用研究应用程序。对照组的患者只参加了访问。主要终点是医院焦虑和抑郁量表(HADS)评分的显著降低。 Secondary end points were reductions in Dermatology Life Quality Index score, Psoriasis Area and Severity Index score, pruritus, and pain, as well as improvements in mood and daily activities. In addition, modulating effects of sex, age, disease duration, and app use frequency were evaluated. Results: A total of 107 patients were included in the study and randomized into the control group (53/107, 49.5%) or intervention group (54/107, 50.5%). Approximately 71.9% (77/107) of the patients completed the study. A significant reduction in HADS-Depression (HADS-D) in the intervention group was found at weeks 12 (P=.04) and 24 (P=.005) but not at weeks 36 (P=.12) and 60 (P=.32). Patient stratification according to app use frequency showed a significant improvement in HADS-D score at weeks 36 (P=.004) and 60 (P=.04) and in HADS-Anxiety (HADS-A) score at weeks 36 (P=.04) and 60 (P=.05) in the group using the app less than once every 5 weeks. However, in patients using the app more than once every 5 weeks, no significant reduction in HADS-D (P=.84) or HADS-A (P=.20) score was observed over the 60-week study period compared with that observed in patients in the control group. All findings were independent of sex, age, and disease duration. Conclusions: These findings support the use of a disease management smartphone app as a valid tool to achieve long-term improvement in the mental health of patients with psoriasis if it is not used too frequently. Further studies are needed to analyze the newly observed influence of app use frequency. Trial Registration: Deutsches Register Klinischer Studien DRKS00020755; https://tinyurl.com/nyzjyvvk %M 34431478 %R 10.2196/28149 %U https://mhealth.www.mybigtv.com/2021/10/e28149 %U https://doi.org/10.2196/28149 %U http://www.ncbi.nlm.nih.gov/pubmed/34431478