mHealth对艾滋病毒感染者抗逆转录病毒治疗依从性的有效性:卡塔尔世界杯8强波胆分析随机对照试验荟萃分析%A孙，Liang %A Qu,Mengbing %A Chen,Bing %A Li,Chuancang %A Fan,Haohao %A Zhao,Yang %+郑州大学公共卫生学院，郑州大学新校区，郑州科学大道100号，中国郑州450001,86 13803845359 zhaomiemie@126.com %K HIV %K mHealth %K抗逆转录病毒治疗%K meta分析%D 2023 %7 23.1.2023 %9 Review %J JMIR mHealth Uhealth %G English %X世界卫生组织建议所有感染艾滋病毒的成年人坚持抗逆转录病毒治疗(ART)。坚持抗逆转录病毒治疗对病人和公众都是有益的。此外，移动医疗在改善全球艾滋病毒药物依从性方面显示出希望。目的:本荟萃分析的目的是分析移动健康对艾滋病毒感染者坚持抗逆转录病毒治疗的有效性。方法:在电子数据库中检索截至2021年12月发表的关于移动医疗与抗逆转录病毒治疗依从性之间关系的随机对照试验(rct)。计算优势比(ORs)、加权平均差异和95% ci。本meta分析采用Mantel-Haenszel方法或逆方差检验。我们用I2统计量评估异质性。 If I2 was ≤50%, heterogeneity was absent, and a fixed effect model was used. If I2 was >50%, heterogeneity was present, and a random effects model was used. Results: A total of 2163 participants in 8 studies were included in this meta-analysis. All included studies were RCTs. The random effects model was used for a meta-analysis of the effects of various intervention measures compared to routine nursing; the outcome was not statistically significant (OR 1.54, 95% CI 0.99-2.38; P=.05). In the subgroups, only short messaging service (SMS)-based interventions significantly increased adherence to ART (OR 1.76, 95% CI 1.07-2.89; P=.03). Further analysis showed that only interactive or bidirectional SMS could significantly increase ART adherence (OR 1.69, 95% CI 1.22-2.34; P=.001). After combining the difference in CD4 cell count before and after the interventions, we concluded that there was no statistical heterogeneity among the studies (I2=0%; tau2=0.37; P=.95). Conclusions: Interactive or bidirectional SMS can enhance intervention effects. However, whether mHealth can improve adherence to ART in patients with HIV needs further study. Owing to a lack of the required significant staff time, training, and ongoing supervision, there is still much more to do to apply mHealth to the clinical use of ART for patients living with HIV. Trial Registration: PROSPERO CRD42022358774; https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=358774 %M 36689267 %R 10.2196/42799 %U https://mhealth.www.mybigtv.com/2023/1/e42799 %U https://doi.org/10.2196/42799 %U http://www.ncbi.nlm.nih.gov/pubmed/36689267