@文章{信息:doi/10.2196/17418，作者=“Twimukye, Adelline和Bwanika Naggirinya, Agnes和parks - ratanshi, Rosalind和Kasirye, Ronnie和Kiragga, Agnes和Castelnuovo, Barbara和Wasswa, Jacob和Nabaggala, Maria Sarah和Katabira, Elly和Lamorde, Mohammed和King, Rachel Lisa”，标题=“在一项随机对照试验中，手机支持工具(乌干达生命呼吁)促进年轻人坚持抗逆转录病毒治疗的可接受性:探索性定性研究”，期刊=“JMIR Mhealth Uhealth”，年=“2021”，月=“6”，日=“14”，卷=“9”，号=“6”，页=“e17418”，关键词=“HIV;移动健康;年轻的成年人;依从性;定性的;乌干达”，摘要=“背景:坚持治疗是成功治疗结果的关键。尽管影响抗逆转录病毒治疗依从性的因素各不相同，但由于耻辱感、与抗逆转录病毒治疗相关的副作用以及缺乏获得治疗的机会等社会心理问题，年轻人坚持治疗的可能性较小。乌干达生命呼吁(CFLU)移动健康(mHealth)工具是一种基于移动电话的技术，通过网络界面提供文本信息或交互式语音响应功能，并提供4个支持模块。目的:本研究旨在通过一项随机对照试验，描述手机支持工具促进年轻人坚持抗逆转录病毒治疗的可接受性和可行性。 Methods: An exploratory qualitative design with a phenomenological approach at 2 study sites was used. A total of 17 purposively selected young adults with HIV infection who had used the mHealth tool CFLU from 2 clinics were included. In total, 11 in-depth interviews and 1 focus group discussion were conducted to examine the following topics: experience with the CFLU tool (benefits and challenges), components of the tool, the efficiency of the system (level of comfort, ease, or difficulty in using the system), how CFLU resolved adherence challenges, and suggestions to improve CFLU. Participants belonged to 4 categories of interest: young adults on ART for the prevention of mother-to-child transmission, young adults switching to or on the second-line ART, positive partners in an HIV-discordant relationship, and young adults initiating the first-line ART. All young adults had 12 months of daily experience using the tool. Data were analyzed using NVivo version 11 software (QSR International Limited) based on a thematic approach. Results: The CFLU mHealth tool was perceived as an acceptable intervention; young adults reported improvement in medication adherence, strengthened clinician-patient relationships, and increased health knowledge from health tips. Appointment reminders and symptom reporting were singled out as beneficial and helped to address the problems of forgetfulness and stigma-related issues. HIV-related stigma was reported by a few young people. Participants requested extra support for scaling up CFLU to make it more youth friendly. Improving the tool to reduce technical issues, including network outages and a period of software failure, was suggested. They suggested that in addition to digital solutions, other support, including the promotion of peer support meetings and the establishment of a designated space and staff members for youth, was also important. Conclusions: This mHealth tool was an acceptable and feasible strategy for improving ART adherence and retention among young adults in resource-limited settings. Trial Registration: ClinicalTrials.gov NCT02953080; https://clinicaltrials.gov/ct2/show/NCT02953080 ", issn="2291-5222", doi="10.2196/17418", url="https://mhealth.www.mybigtv.com/2021/6/e17418", url="https://doi.org/10.2196/17418", url="http://www.ncbi.nlm.nih.gov/pubmed/34121665" }