@文章{信息:doi/10.2196/16696，作者=“Dorsch, Michael P和Cornellier, Maria L和Poggi, Armella D和Bilgen, Feriha和Chen, Peiyu和Wu, Cindy和An, Lawrence C和Hummel, Scott L”，标题=“一种新型情境即时移动应用程序干预(LowSalt4Life)对成人高血压患者钠摄入量的影响:试点随机对照试验”，期刊=“JMIR Mhealth Uhealth”，年=“2020”，月=“8”，日=“10”，卷=“8”，数=“8”，页=“e16696”，关键词=“高血压;钠的摄入;地理围墙;背景:高膳食钠摄入量是美国一个重要的公共卫生问题。高钠摄入量与高血压和心血管疾病的高风险有关。目的:本研究的目的是评估即时适应性移动应用程序干预，即LowSalt4Life，对减少成人高血压患者钠摄入量的影响。方法:本研究采用单中心、前瞻性、开放标签随机对照试验，将50名年龄≥18岁、正在接受高血压治疗的患者随机(1:1，按性别分层)分为App组(LowSalt4Life干预)和No App组(常规饮食建议)2组，为期8周。主要终点是使用川崎方程估计的24小时尿钠排泄量的变化，使用非配对双侧t检验进行分析。次要结果包括通过食物频率问卷(FFQ)测量的钠摄入量的变化，24小时尿钠排泄量，血压水平和自我报告的低钠饮食的信心。结果:从基线到第8周，App组与No App组相比，根据尿样计算的kawasaki估计24小时尿钠排泄量显著减少(分别为-462 [SD 1220] mg和381 [SD 1460] mg; P=.03). The change in the 24-hour urinary sodium excretion was --637 (SD 1524) mg in the App group and --322 (SD 1485) mg in the No App group (P=.47). The changes in the estimated sodium intake as measured by 24-hour dietary recall and by FFQ in the App group were --1537 (SD 2693) mg and --1553 (SD 1764) mg while those in the No App group were --233 (SD 2150) mg and --515 (SD 1081) mg, respectively (P=.07 and P=.01, respectively). The systolic blood pressure change from baseline to week 8 in the App group was --7.5 mmHg while that in the No App group was --0.7 mmHg (P=.12), but the self-confidence in following a low-sodium diet was not significantly different between the 2 groups. Conclusions: This study shows that a contextual just-in-time mobile app intervention resulted in a greater reduction in the dietary sodium intake in adults with hypertension than that in the control group over a 8-week period, as measured by the estimated 24-hour urinary sodium excretion from spot urine and FFQ. The intervention group did not show a significant difference from the control group in the self-confidence in following a low sodium diet and in the 24-hour urinary sodium excretion or dietary intake of sodium as measured by the 24-hour dietary recall. A larger clinical trial is warranted to further elucidate the effects of the LowSalt4Life intervention on sodium intake and blood pressure levels in adults with hypertension. Trial Registration: ClinicalTrials.gov NCT03099343; https://clinicaltrials.gov/ct2/show/NCT03099343 International Registered Report Identifier (IRRID): RR2-10.2196/11282 ", issn="2291-5222", doi="10.2196/16696", url="http://mhealth.www.mybigtv.com/2020/8/e16696/", url="https://doi.org/10.2196/16696", url="http://www.ncbi.nlm.nih.gov/pubmed/32663139" }