@文章{信息:doi/10.2196/30602，作者="索尔森，艾达·K和杨，燕香和瓦伦蒂纳，劳拉·斯陶恩和Gl{"u}mer，夏洛特和Karstoft，克里斯蒂安和Br{o}nd，简·克里斯蒂安和尼尔森，拉斯马斯·厄斯特加德和Br{o}ns，夏洛特和克里斯滕森，罗宾和尼尔森，延斯·斯蒂恩和瓦格，艾伦·亚瑟和Pedersen，本特·克拉伦德和朗伯格，亨宁和里德-拉森，马蒂亚斯"，标题=“InterWalk智能手机应用程序支持的生活方式干预对增加2型糖尿病患者体力活动的影响:平行组，随机试验”，期刊=“JMIR Mhealth Uhealth”，年=“2022”，月=“Sep”，日=“28”，卷=“10”，数=“9”，页=“e30602”，关键词=“2型糖尿病;锻炼;远程医疗;初级保健;个加速器;生活质量;腰围;移动健康;背景:在2型糖尿病(T2D)医疗保健中有效和可持续地实施体育活动(PA)通常并不成功。 Efficacious and contemporary approaches to support PA adherence and adoption are required. Objective: The primary objective of this study was to investigate the effectiveness of including an app-based (InterWalk) approach in municipality-based rehabilitation to increase moderate-and-vigorous PA (MVPA) across 52 weeks compared with standard care among individuals with T2D. Methods: The study was designed as a parallel-group, randomized trial with 52 weeks' intervention and subsequent follow-up for effectiveness (52 weeks from baseline). Participants were recruited between January 2015 and December 2016 and randomly allocated (2:1) into 12 weeks of (1) standard care + InterWalk app--based interval walking training (IWT; IWT group; n=140), or (2) standard care + the standard exercise program (StC group; n=74). Following 12 weeks, the IWT group was encouraged to maintain InterWalk app--based IWT (3 times per week for 30-60 minutes) and the StC group was encouraged to maintain exercise without structured support. Moreover, half of the IWT group (IWTsupport group, n=54) received additional motivational support following the 12-week program until 52-week follow-up. The primary outcome was change in objectively measured MVPA time (minutes/day) from baseline to 52-week follow-up. Key secondary outcomes included changes in self-rated physical and mental health--related quality of life (HRQoL), physical fitness, weight, and waist circumference. Results: Participants had a mean age of 59.6 (SD 10.6) years and 128/214 (59.8{\%}) were men. No changes in MVPA time were observed from baseline to 52-week follow-up in the StC and IWT groups (least squares means [95{\%} CI] 0.6 [--4.6 to 5.8] and --0.2 [--3.8 to 3.3], respectively) and no differences were observed between the groups (mean difference [95{\%} CI] --0.8 [--8.1 to 6.4] minutes/day; P=.82). Physical HRQoL increased by a mean of 4.3 (95{\%} CI 1.8 to 6.9) 12-item Short-Form Health Survey (SF-12) points more in the IWT group compared with the StC group (Benjamini-Hochberg adjusted P=.007) and waist circumference apparently decreased a mean of --2.3 (95{\%} CI --4.1 to --0.4) cm more in the IWT group compared with the StC group but with a Benjamini-Hochberg adjusted P=.06. No between-group differences were observed among the remaining key secondary outcomes. Conclusions: Among individuals with T2D referred to municipality-based lifestyle programs, randomization to InterWalk app--based IWT did not increase objectively measured MVPA time over 52 weeks compared with standard health care, although apparent benefits were observed for physical HRQoL. Trial Registration: ClinicalTrials.gov NCT02341690; https://clinicaltrials.gov/ct2/show/NCT02341690 ", issn="2291-5222", doi="10.2196/30602", url="https://mhealth.www.mybigtv.com/2022/9/e30602", url="https://doi.org/10.2196/30602", url="http://www.ncbi.nlm.nih.gov/pubmed/36170002" }