TY -的AU -金纳德,丹尼尔AU -水列夫,迈克尔•AU -帕蒂尔Bhagyashree AU -沃尔什,梅根AU -凯恩,约翰M PY - 2022 DA - 2022/10/12 TI -数字使用日常财政激励措施提高药物依从性干预严重精神疾病:单臂纵向试点研究乔- JMIR表示“状态”健康SP - e37184六世- 9 - 10 KW -抗精神病KW -坚持KW -数字KW -移动健康KW - mHealth KW -财务激励AB -背景:药物不依从在严重的精神疾病中普遍存在，并与多种负面结果相关。移动技术和财务激励显示出改善服药依从性的前景;然而，心理健康方面的研究，尤其是口服药物方面的研究，目前还缺乏。目的:本文旨在评估基于行为经济学原理，通过手机应用程序提供财务激励以改善严重精神疾病患者的药物依从性的可行性和有效性。方法:进行为期10周的单臂纵向试验研究。患者在基于应用程序的坚持激励下获得奖励。奖励分为每两周支付15美元，减去每天因未签到而受到的2美元罚款。采用时变效应模型来总结患者在研究过程中的反应。结果:共纳入25例患者，其中72% (n=18)为女性，48% (n=12)为白人。 Median age was 24 (Q1-Q3: 20.5-30) years. Participants were more frequently diagnosed with schizophrenia and related disorders (n=9, 36%), followed by major depressive disorder (n=8, 32%). App engagement and medication adherence in the first 2 weeks were higher than in the last 8 weeks of the study. At study endpoint, app engagement remained high (n=24, Z=–3.17; P<.001), but medication adherence was not different from baseline (n=24, Z=–0.59; P=.28). Conclusions: Financial incentives were effectively delivered using an app and led to high engagement throughout the study and a significantly increased medication adherence for 2 weeks. Leveraging behavioral economics and mobile health technology can increase medication adherence in the short term. Trial Registration: ClinicalTrials.gov NCT04191876; https://clinicaltrials.gov/ct2/show/NCT04191876 SN - 2368-7959 UR - https://mental.www.mybigtv.com/2022/10/e37184 UR - https://doi.org/10.2196/37184 UR - http://www.ncbi.nlm.nih.gov/pubmed/36222818 DO - 10.2196/37184 ID - info:doi/10.2196/37184 ER -