%0杂志文章%@ 2368-7959 %I JMIR出版物%V 9% 卡塔尔世界杯8强波胆分析N 10% P e37184% T使用日常经济激励来增加严重精神疾病患者的药物依从性的数字干预:单臂纵向试验研究%A Guinart,Daniel %A Sobolev,Michael %A Patil,Bhagyashree %A Walsh,Megan %A Kane,John M %+精神病科，The Zucker Hillside Hospital, 75-59, Glen Oaks, NY, 11004，美国，1 7184704139,daniguinart@gmail.com %K抗精神病药%K坚持%K数字%K移动健康%K mHealth %K财务激励%D 2022 %7 12.10.2022 %9短论文%J JMIR Ment health %G英语%X背景:药物不依从在严重的精神疾病中普遍存在，并与多种负面结果相关。移动技术和财务激励显示出改善服药依从性的前景;然而，心理健康方面的研究，尤其是口服药物方面的研究，目前还缺乏。目的:本文旨在评估基于行为经济学原理，通过手机应用程序提供财务激励以改善严重精神疾病患者的药物依从性的可行性和有效性。方法:进行为期10周的单臂纵向试验研究。患者在基于应用程序的坚持激励下获得奖励。奖励分为每两周支付15美元，减去每天因未签到而受到的2美元罚款。采用时变效应模型来总结患者在研究过程中的反应。 Results: A total of 25 patients were enrolled in this pilot study, of which 72% (n=18) were female, and 48% (n=12) were of a White racial background. Median age was 24 (Q1-Q3: 20.5-30) years. Participants were more frequently diagnosed with schizophrenia and related disorders (n=9, 36%), followed by major depressive disorder (n=8, 32%). App engagement and medication adherence in the first 2 weeks were higher than in the last 8 weeks of the study. At study endpoint, app engagement remained high (n=24, Z=–3.17; P<.001), but medication adherence was not different from baseline (n=24, Z=–0.59; P=.28). Conclusions: Financial incentives were effectively delivered using an app and led to high engagement throughout the study and a significantly increased medication adherence for 2 weeks. Leveraging behavioral economics and mobile health technology can increase medication adherence in the short term. Trial Registration: ClinicalTrials.gov NCT04191876; https://clinicaltrials.gov/ct2/show/NCT04191876 %M 36222818 %R 10.2196/37184 %U https://mental.www.mybigtv.com/2022/10/e37184 %U https://doi.org/10.2196/37184 %U http://www.ncbi.nlm.nih.gov/pubmed/36222818