%0期刊文章%@ 2368- 7959% I JMIR出版物%V 3%卡塔尔世界杯8强波胆分析 N 4% P e52% T创建实时互动以减轻障碍(CLIMB):移动干预改善慢性精神障碍患者的社会功能%A Biagianti,Bruno %A Schlosser,Danielle %A Nahum,Mor %A Woolley,Josh %A Vinogradov,Sophia %+加州大学旧金山分校精神病学系，401 Parnassus Avenue l2 -253，旧金山，CA, 94143，美国，1 4152902122，bruno.biagianti@ucsf.edu %K精神病%K社会认知%K数字健康%K移动健康%D 2016 %7 13.12.2016 %9原始论文%J JMIR Ment health %G英文%X背景:对慢性精神障碍(CPD)个体的大量心理社会干预已显示出对社会认知和功能结果测量的积极影响。然而，这些干预措施的获取和参与仍然有限。这在一定程度上是因为这些干预措施需要经过专门培训的治疗师，并不是在所有的临床环境中都有，并且对参与者有很高的日程安排负担，通常需要几周的承诺。通过移动设备远程提供干预措施可以促进访问，提高日程安排的灵活性，并减少参与者的负担，从而提高对干预要求的依从性。为了满足这些需求，我们设计了创建实时互动以减轻障碍(CLIMB)数字干预，旨在增强CPD患者的社交功能。CLIMB包括两个治疗部分:计算机化社会认知训练(SCT)程序和优化的远程团体治疗(ORGT)。ORGT是一种创新的治疗方法，它将远程群体治疗与群体短信(短信服务)相结合。目的:这项单臂研究的目的是调查对持续肾病患者进行6周CLIMB治疗的可行性，并探讨其对结果的初步影响。 Methods: Participants were recruited, screened and enrolled via the Internet, and delivered assessments and interventions remotely using provided tablets (iPads). Participants were asked to complete 18 hours of SCT and to attend 6 remote group therapy sessions. To assess feasibility, adherence to study procedures, attrition rates, engagement metrics, and acceptability of the intervention were evaluated. Changes on measures of social cognition, quality of life, and symptoms were also explored. Results: In total, 27 participants were enrolled over 12 months. Remote assessments were completed successfully on 96% (26/27) of the enrolled participants. Retention in the 6-week trial was 78% (21/27). Of all the iPads used, 95% (22/23) were returned undamaged at the end of the intervention. Participants on average attended 84% of the group therapy sessions, completed a median of 9.5 hours of SCT, and posted a median of 5.2 messages per week on the group text chat. Participants rated CLIMB in the medium range in usability, acceptability, enjoyment, and perceived benefit. Participants showed significant improvements in emotion identification abilities for prosodic happiness (P=.001), prosodic happiness intensity (P=.04), and facial anger (P=.04), with large within-group effect sizes (d=.60 to d=.86). Trend-level improvements were observed on aspects of quality of life (P values less than .09). No improvements were observed for symptoms. Conclusions: It is feasible and acceptable to remotely deliver an intervention aimed at enhancing social functioning in people with CPD using mobile devices. This approach may represent a scalable method to increase treatment access and adherence. Our pilot data also demonstrate within-group gains in some aspects of social cognition after 6 weeks of CLIMB. Future randomized controlled studies in larger samples should evaluate the extent to which CLIMB significantly improves social cognition, symptoms, and quality of life in CPD. %M 27965190 %R 10.2196/mental.6671 %U http://mental.www.mybigtv.com/2016/4/e52/ %U https://doi.org/10.2196/mental.6671 %U http://www.ncbi.nlm.nih.gov/pubmed/27965190