@文章{信息:doi/10.2196/37184，作者=“Guinart, Daniel和Sobolev, Michael和Patil, Bhagyashree和Walsh, Megan和Kane, John M”，标题=“使用日常财务激励来增加严重精神疾病药物依从性的数字干预:单臂纵向试验研究”，期刊=“JMIR Ment Health”，年=“2022”，月=“10月”，日=“12”，卷=“9”，数=“10”，页=“e37184”，关键词=“抗精神病药;依从性;数字;移动健康;移动健康;背景:药物不依从在严重精神疾病中普遍存在，并与多种负面结果相关。移动技术和财务激励显示出改善服药依从性的前景;然而，心理健康方面的研究，尤其是口服药物方面的研究，目前还缺乏。目的:本文旨在评估基于行为经济学原理，通过手机应用程序提供财务激励以改善严重精神疾病患者的药物依从性的可行性和有效性。方法:进行为期10周的单臂纵向试验研究。 Patients earned rewards in the context of app-based adherence incentives. The reward was split into biweekly payments made in increments of US {\$}15, minus any US {\$}2 per day penalties for missed check-ins. Time-varying effect modeling was used to summarize the patients' response during the study. Results: A total of 25 patients were enrolled in this pilot study, of which 72{\%} (n=18) were female, and 48{\%} (n=12) were of a White racial background. Median age was 24 (Q1-Q3: 20.5-30) years. Participants were more frequently diagnosed with schizophrenia and related disorders (n=9, 36{\%}), followed by major depressive disorder (n=8, 32{\%}). App engagement and medication adherence in the first 2 weeks were higher than in the last 8 weeks of the study. At study endpoint, app engagement remained high (n=24, Z=--3.17; P<.001), but medication adherence was not different from baseline (n=24, Z=--0.59; P=.28). Conclusions: Financial incentives were effectively delivered using an app and led to high engagement throughout the study and a significantly increased medication adherence for 2 weeks. Leveraging behavioral economics and mobile health technology can increase medication adherence in the short term. Trial Registration: ClinicalTrials.gov NCT04191876; https://clinicaltrials.gov/ct2/show/NCT04191876 ", issn="2368-7959", doi="10.2196/37184", url="https://mental.www.mybigtv.com/2022/10/e37184", url="https://doi.org/10.2196/37184", url="http://www.ncbi.nlm.nih.gov/pubmed/36222818" }