@文章{info:doi/10.2196/33871，作者="McIntyre, Roger S和Lipsitz, Orly和Rodrigues, Nelson B和Subramaniapillai, Mehala和Nasri, Flora和Lee, Yena和Fehnert, Ben和King, James和Chrones, Lambros和Kratiuk, Kevin和Uddin, Sharif和Rosenblat, Joshua D和Mansur, Rodrigo B和McCue, Maggie"，标题="基于应用程序的数字符号替换测试评估成人重度抑郁障碍的认知缺陷:评价研究"，期刊="JMIR Ment Health"，年="2022"，月="10"，日="27"，卷="9"，数="10"，页="e33871"，关键词="抑郁症;DSST;数字符号替换检验;智能手机;技术;计量护理;背景:认知功能障碍是抑郁症的核心症状之一。在接受抗抑郁药物治疗的成人重度抑郁障碍(MDD)中，残余的认知症状会干扰患者报告的结果。上述认知症状的描述为在护理点筛查和评估认知症状的严重程度提供了基础。 However, clinical neurocognitive assessments are time-consuming and difficult, and they require specialist expertise to interpret them. A smartphone-delivered neurocognitive test may offer an effective and accessible tool that can be readily implemented into a measurement-based care framework. Objective: We aimed to evaluate the use of a smartphone-delivered app-based version of the established Cognition Kit Digit Symbol Substitution Test (DSST) neurocognitive assessment compared to a traditional paper-and-pencil version. Methods: Convergent validity and test-retest reliability of the 2 versions were evaluated. Patient satisfaction with the app was also assessed. Results: Assessments made using the app-based Cognition Kit DSST were highly correlated with the standard paper-and-pencil version of the test, both at the baseline visit (r=0.69, df=27; P<.001) and at the end-of-study visit (r=0.82, df=27; P<.001), and they were positively evaluated by 30 patients as being user-friendly, easy to navigate, and preferable over the paper-and-pencil version of the DSST. However, although the app-based Cognition Kit DSST was validated in patients with MDD, it still needs to be evaluated in healthy controls. Conclusions: App-based DSST may facilitate a more personalized, convenient, and cost-effective method of cognitive assessment, helping to guide measurement-based care and psychotherapeutic and pharmacologic treatment options for patients with MDD. Trial Registration: ClinicalTrials.gov NCT03999567; https://tinyurl.com/2p8pnyv7 ", issn="2368-7959", doi="10.2196/33871", url="https://mental.www.mybigtv.com/2022/10/e33871", url="https://doi.org/10.2196/33871", url="http://www.ncbi.nlm.nih.gov/pubmed/36301615" }