@Article{info:doi/10.2196/26665，作者=“Ha{\ss}denteufel, Kathrin and Lingenfelder, Katrin and Schwarze, Cornelia E and Feisst, Manuel and Brusniak, Katharina and Matthies, Lina Maria and Goetz, Maren and Wallwiener, Markus and Wallwiener, Stephanie”，标题=“基于网络的重复筛查预测产后抑郁症的评估:前瞻性队列研究”，期刊=“JMIR Ment Health”，年=“2021”，月=“Dec”，日=“10”，卷=“8”，号=“12”，页=“e26665”，关键词=“产后抑郁症;爱丁堡产后抑郁量表;筛选;怀孕;背景:产后抑郁症(Postpartum depression, PPD)是一种严重的精神障碍，常导致母婴依恋不良，对婴儿发育产生负面影响。最近建议进行普遍筛查以确定有风险的妇女，但迄今为止尚未确定怀孕期间的最佳筛查时间。因此，在育龄妇女中广泛使用的网络技术为在早期阶段发现具有不良心理健康后果高风险的妊娠创造了新的机会。目的:本研究的目的是通过使用基于网络的筛查工具收集电子患者报告结果(ePROs)作为筛查算法的基础，对妊娠期间PPD的风险进行分层，并确定最佳筛查时间。方法:共有214名妇女在怀孕期间和怀孕后分别使用爱丁堡产后抑郁量表(EPDS)进行了5次和3次抑郁症状的反复测试，EPDS可在本研究作者开发的基于网络的妊娠平台上访问。 For each prenatal assessment, the area under the curve (AUC), sensitivity, specificity, and predictive values for PPD were calculated. Multivariate logistic regression analyses were applied to identify further potential predictors, such as age, education, parity, relationship quality, and anxiety, to increase predictive accuracy. Results: Digitally collected data from 214 pregnant women were analyzed. The predictive accuracy of depressive symptoms 3 and 6 months postpartum was reasonable to good regarding the screening in the second (AUC=0.85) and third (AUC=0.75) trimester. The multivariate logistic regression analyses resulted in an excellent AUC of 0.93 at 3 months and a good AUC of 0.87 at 6 months postpartum. Conclusions: The best predictive accuracy for PPD has been shown for screening between the 24th and the 28th gestational week (GW) and seems to be beneficial for identifying women at risk. In combination with the aforementioned predictive factors, the discriminatory power improved, particularly at 3 months postpartum. Screening for depression during pregnancy, combined with the women's personal risk profile, can be used as a starting point for developing a digital screening algorithm. Thereby, web-based assessment tools constitute feasible, efficient, and cost-effective approaches. Thus, they seem to be beneficial in detecting high-risk pregnancies in order to improve maternal and infant birth outcomes in the long term. ", issn="2368-7959", doi="10.2196/26665", url="https://mental.www.mybigtv.com/2021/12/e26665", url="https://doi.org/10.2196/26665", url="http://www.ncbi.nlm.nih.gov/pubmed/34890349" }