%0期刊文章%@ 2369-3762 %I JMIR出版物%V 4% 卡塔尔世界杯8强波胆分析N 2% P e10347% T使用分级推荐，评估，发展和评估来打击假新闻:妊娠流感疫苗接种的案例研究%A Zafar,Sidra %A Habboush,Yacob %A Beidas, ary %+内科，橘子公园医疗中心，2001金斯利大道，橘子公园，杰克逊维尔，佛罗里达州，32073，美国，1 904 639 8500,sary.beidas@hcahealthcare.com %K GRADE %K流感%K疫苗%K自然流产%K流产%D 2018 %7 07.11.2018 %9回顾%J JMIR Med Educ %G英文%X背景:推荐、评估、发展和评价分级(GRADE)框架是一个经过验证的评估工具，用于评估科学出版物的质量。它有助于加强临床医生的决策过程，并支持制定知情的健康政策。目的:本报告有两个目的。首先，我们回顾了观察性研究的解释。第二个目的是分享或提供一个使用GRADE标准的示例。方法:为了说明使用GRADE框架评估出版物，我们选择了一项评估流感疫苗接种后自然流产(SAB)风险的研究。结果:自2004年以来，疾病控制和预防中心和免疫实践咨询委员会建议孕妇接种流感疫苗。以前的研究没有发现流感疫苗接种与SAB之间的关联。 However, in a recent case-control study by Donahue et al, a correlation with SAB in women who received the H1N1 influenza vaccine was identified. For women who received H1N1–containing vaccine in the previous and current influenza season, the adjusted odds ratio (aOR) for SAB was 7.7 (95% CI, 2.2-27.3), while the aOR for women not vaccinated in the previous season but vaccinated in the current season was 1.3 (95% CI, 0.7-2.7). Conclusions: Our goal is to enable the readers to critique published literature using appropriate evaluation tools such as GRADE. %M 30404772 %R 10.2196/10347 %U http://mededu.www.mybigtv.com/2018/2/e10347/ %U https://doi.org/10.2196/10347 %U http://www.ncbi.nlm.nih.gov/pubmed/30404772