I JMIR出版物V 12% N 2% P e14973 %T耐甲氧西卡塔尔世界杯8强波胆分析林金黄色葡萄球菌根除和去殖儿童研究(第二部分):非殖民地化以病人和父母为中心的结果摩尔，考特尼·维赫，莎拉·林奇，达斯汀·克莱斯顿，吉娜·兰曼，马修·卡罗尔，亚伦·穆西，保罗·保罗+印第安纳大学医学院急诊医学系急诊医学系，印第安纳波利斯埃斯肯纳兹大道720号第五第三银行大楼三楼|，邮号:1 678 358 9814，邮号:46202，pmusey@iu.edu %K以患者为中心的结果%K金黄色葡萄球菌%K脓肿%K去殖民化%K以人为中心的设计%D 2020 %7 20.5.2020 %9原始论文%J J参与者医学%G英语%X背景:由社区获得性耐甲氧西林金黄色葡萄球菌(MRSA)引起的皮肤和软组织感染(SSTIs)可导致许多已知的重大医疗后果，包括住院、外科手术，如切口和引流(I&D)，以及需要进行去殖民化手术以清除皮肤和鼻子中的细菌并防止复发感染。关于MRSA感染的成功治疗与以患者和护理人员为中心的结果相关的研究很少。目的:本研究旨在揭示对患者及其父母重要的MRSA去殖民化结果，以便创建一套用于儿童MRSA根除和去殖民化(MEDiC)研究的原型措施。方法:以人为本的设计(HCD)研讨会进行了4小时，5名10-18岁的青少年(10-18岁)和11名儿童的父母进行了I&D手术。研讨会探讨了皮肤感染的患者和家庭经验，以揭示MRSA治疗以患者为中心的结果。研究团队分析了研讨会期间产生的音频和人工制品，并对主题相似性进行编码。最后的主题代表了在MEDiC比较有效性试验中测量的以患者为中心的结果域。 Results: The workshop identified 9 outcomes of importance to patients and their parents: fewer MRSA outbreaks, improved emotional health, improved self-perception, decreased social stigma, increased amount of free time, increased control over free time, fewer days of school or work missed, decreased physical pain and discomfort, and decreased financial burden. Conclusions: This study represents an innovative HCD approach to engaging patients and families with lived experience with MRSA SSTIs in the study design and trial development to determine meaningful patient-centered outcomes. We were able to identify 9 major recurrent themes. These themes were used to develop the primary and secondary outcome measures for MEDiC, a prospectively enrolling comparative effectiveness trial. Trial Registration: ClinicalTrials.gov NCT02127658; https://clinicaltrials.gov/ct2/show/NCT02127658 %R 10.2196/14973 %U http://jopm.www.mybigtv.com/2020/2/e14973/ %U https://doi.org/10.2196/14973