TY - JOUR AU - Bu，吴晓凡AU - Ng, Peter H F AU - Xu, AU - Cheng文静，AU - Chen Qinqin, Peter Q AU - Cheng, Andy S K AU - Liu, Xiangyu PY - 2022 DA - 2022/2/28 TI -基于虚拟现实的干预在乳腺癌幸存者康复管理中的有效性:JO - JMIR Serious Games SP - e31395 VL - 10 IS - 1kw -虚拟现实KW -康复管理KW -症状KW -运动功能KW -系统回顾KW -元分析AB -背景:乳腺癌幸存者(BCSs)可以表现出影响其生活质量的各种生理和心理症状和功能缺陷。虚拟现实(VR)技术正被用于乳腺癌康复管理，以改善bcs的情感、认知和身体健康。目的:本系统综述旨在研究基于虚拟现实的干预措施对bcs健康相关结局的有效性。我们进行了一项meta分析，以评估基于vr的干预措施在bcs康复管理中的有效性。方法:系统检索PubMed、Web of Science、EMBASE、CINAHL with Full Text、Cochrane Central Register of Controlled Trials、中国知网(CNKI)、万方(WanFang)、维普(VIP)、CBM等网站自创建至2021年5月25日。入选研究的入选标准如下:(1)被诊断为乳腺癌的成年人;(2)任何类型的基于虚拟现实的干预(沉浸式和非沉浸式虚拟环境);(3)传统康复方法的比较;(4)治疗期间和治疗后的结果包括疼痛、抑郁、焦虑、疲劳、认知功能、肩部活动度(ROM)、握力、淋巴水肿、晕动症症状、运动恐惧、出血、积液和皮瓣坏死; and (5) randomized controlled trials (RCTs), case-controlled trials, and quasi-experimental studies. The Cochrane Collaboration Tool was used to evaluate the risk of bias. Review Manager version 5.3 (Cochrane Collaboration) was used to conduct the meta-analysis. The mean difference (MD) and SDs with 95% CIs were used to calculate continuous variables. Results: Twelve articles were included in this systematic review, of which 10 contributed information to the meta-analysis. A total of 604 participants were analyzed. The statistical analysis showed significant results for flexion (standard mean difference [SMD] 1.79; 95% CI 0.55 to 3.03; P=.005), extension (SMD 1.54; 95% CI 0.83 to 2.25; P<.001), abduction (MD 17.53; 95% CI 14.33 to 20.72; P<.001), adduction (MD 15.98; 95% CI 14.02 to 17.94; P<.001), internal rotation (MD 7.12; 95% CI 5.54 to 8.70; P<.001), external rotation (SMD 0.96; 95% CI 0.62 to 1.29; P<.001), anxiety (MD −6.47; 95% CI −7.21 to −5.73; P<.001), depression (MD −4.27; 95% CI −4.64 to −3.91; P<.001), pain (MD −1.32; 95% CI −2.56 to −0.09; P=.04), and cognitive function (MD 8.80; 95% CI 8.24 to 9.36; P<.001). The meta-analysis indicated little to no difference in hand grip strength (MD 1.96; 95% CI –0.93 to 4.85; P=.18). Conclusions: Findings of this review noted a weak but consistent positive association between VR-based interventions and outcomes. However, these results must be interpreted with caution due to the limited number of controlled trials analyzed, small sample sizes, and poor methodological quality. Well‐designed, large, high‐quality trials may have a significant impact on our confidence in the results. Future studies should identify specific aspects that improve the clinical impact of VR-based interventions on major outcomes in BCSs in the clinical setting. Trial Registration: PROSPERO International Prospective Register of Systematic Reviews CRD42021250727; https://tinyurl.com/2p89rmnk SN - 2291-9279 UR - https://games.www.mybigtv.com/2022/1/e31395 UR - https://doi.org/10.2196/31395 UR - http://www.ncbi.nlm.nih.gov/pubmed/35225817 DO - 10.2196/31395 ID - info:doi/10.2196/31395 ER -