TY - JOUR AU - Wu, AU - Zhang金龙，AU - Chen慧，AU - Fu紫燕，AU - Yang瑞佳，Hao AU - Zeng, AU -任宏发，占兵PY - 2022 DA - 2022/3/1 TI -虚拟现实平衡训练对帕金森病患者的益处:系统回顾、分析和多元回归的随机对照试验乔- JMIR严肃游戏SP - e30882六世- 10 - 1 KW -虚拟现实KW -帕金森病KW -平衡千瓦系统回顾KW -荟萃分析KW -多元回归KW -严肃游戏KW - VR KW -康复KW -虚拟现实训练AB -背景:虚拟现实(VR)平衡训练在生物医学研究中越来越多的追求,特别是对调查平衡能力与虚拟现实。然而，现有的系统综述发现VR在改善帕金森病(PD)患者平衡能力方面的疗效结论不一致。目的:评价VR平衡训练对帕金森病患者平衡能力的影响。方法:检索所有主要数据库，包括Web of Science、PubMed、Scopus、China National Knowledge Infrastructure和Wanfang，以确定自2010年9月15日以来所有以英文或中文发表的相关研究。两名研究人员独立进行了文献检索、研究选择、数据提取和方法学质量评价。结果:共分析了16项随机对照试验(n=583例PD患者)，方法学质量评价评分为5 ~ 8分。选择随机效应模型来组合效应大小。meta分析显示，与对照组相比，VR训练后PD的平衡能力明显改善(标准化平均差[SMD] 2.127, 95% CI 1.202 ~ 3.052, P<。001, I2=95.1, df=15)。值得注意的是，干预平台可能是异质性的主要原因。 Meta regression analysis showed that no training program could predict the impact of VR training (P=.57 to .94) on PD balance ability. Subgroup result showed that a single training time of 0 to 20 minutes (SMD 6.446), 4 to 6 times per week (SMD 4.067), training for 3 to 5 weeks (SMD 62.478), training course reached more than 30 times (SMD 4.405), and 201 to 300 minutes per week (SMD 4.059) maybe have more benefit. Conclusions: A systematic review and meta-analysis confirmed that VR balance training is a highly effective means to improve balance performance with large effects in PD. In addition, we preliminarily extracted dose-effect relationships for training volume, informing clinicians and practitioners to design effective VR balance training for balance ability. Further research is needed to reveal optimal dose-response relationships following VR balance training. SN - 2291-9279 UR - https://games.www.mybigtv.com/2022/1/e30882 UR - https://doi.org/10.2196/30882 UR - http://www.ncbi.nlm.nih.gov/pubmed/35230242 DO - 10.2196/30882 ID - info:doi/10.2196/30882 ER -