%0期刊文章%@ 2291- 9279% I JMIR出版物%V 10卡塔尔世界杯8强波胆分析% N 2% P e34402 %T虚拟现实在慢性疼痛管理中的应用:系统评价和元分析%A古德曼，Lisa %A Jansen,Julie %A Billot,Maxime %A Vets,Nieke %A De Smedt,Ann %A Roulaud,Manuel %A Rigoard,Philippe %A Moens,Maarten %+ STIMULUS，布鲁塞尔自由大学，Laarbeeklaan 103, jeette, 1090，比利时，32 2477 5514，lisa.goudman@gmail.com %K虚拟现实%K慢性疼痛%K系统综述%K多层元分析%K沉浸式技术%K临床结果%K手机%D 2022 %7 10.5.2022 %9综述%J JMIR严肃游戏%G英文%X背景:虚拟现实(VR)是一种让用户沉浸在完全不同的现实中的计算机技术。VR在急性疼痛中的应用已经得到了很好的证实。然而，在慢性疼痛中，VR的应用和结果参数不太清楚。目的:本综述旨在系统地确定所有已报道的与慢性疼痛患者VR相关的结局参数。方法:检索PubMed、Scopus、Web of Science、Embase 4个电子数据库进行相关研究。进行多水平随机效应荟萃分析，其中选择标准化的平均差异作为效应大小，以表示VR干预前后测量之间的差异。结果:最初的数据库检索确定了1430项研究，其中41项(2.87%)最终纳入了系统评价。有证据表明VR对疼痛、功能、机动性、功能能力、心理结果、生活质量、神经心理学结果和身体感觉的影响。 The overall effect size (a total of 194 effect sizes from 25 studies) based on a three level meta-analysis was estimated at 1.22 (95% CI 0.55-1.89; z=3.56; P<.001), in favor of improvements after a VR intervention. When categorizing effect sizes, the overall effect sizes were reported as follows: 1.60 (95% CI 0.83-2.36; z=4.09; P<.001) for the effect of VR on pain (n=31), 1.40 (95% CI 0.13-2.67; z=2.17; P=.03) for functioning (n=60), 0.49 (95% CI −0.71 to 1.68; z=0.80; P=.42) for mobility (n=24), and 0.34 (95% CI −1.52 to 2.20; z=0.36; P=.72) for functional capacity (n=21). Conclusions: This systematic review revealed a broad range of outcome variables influenced by an intervention of VR technology, with statistically significant pain relief and improvements in functioning. These findings indicate that VR not only has applications in acute pain management but also in chronic pain settings, whereby VR might be able to become a promising first-line intervention as complementary therapy for patients with chronic pain. Trial Registration: PROSPERO International Prospective Register of Systematic Reviews CRD42021227016; https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=227016 %M 35536641 %R 10.2196/34402 %U https://games.www.mybigtv.com/2022/2/e34402 %U https://doi.org/10.2196/34402 %U http://www.ncbi.nlm.nih.gov/pubmed/35536641