%0杂志文章%@ 2291- 9279% I JMIR出版物%V 10卡塔尔世界杯8强波胆分析% N 1% P e30882% T虚拟现实平衡训练对帕金森病患者的好处:一项随机对照试验的系统综述、meta分析和meta回归% a吴金龙% a张辉% a陈辉% a付子燕% a杨瑞佳% a曾浩% a任宏发% a占兵%+深圳大学体育系，深圳南海路3588号，518060,86 13318881919rzb@szu.edu.cn %K虚拟现实%K帕金森病%K平衡%K系统回顾%K元分析%K元回归%K严肃游戏%K VR %K康复%K VR训练%D 2022 %7 1.3.2022 %9回顾%J JMIR严肃游戏%G英语%X背景:虚拟现实(VR)平衡训练越来越多地被用于生物医学研究，特别是关于用VR研究平衡能力。然而，现有的系统综述发现VR在改善帕金森病(PD)患者平衡能力方面的疗效结论不一致。目的:评价VR平衡训练对帕金森病患者平衡能力的影响。方法:检索所有主要数据库，包括Web of Science、PubMed、Scopus、China National Knowledge Infrastructure和Wanfang，以确定自2010年9月15日以来所有以英文或中文发表的相关研究。两名研究人员独立进行了文献检索、研究选择、数据提取和方法学质量评价。结果:共分析了16项随机对照试验(n=583例PD患者)，方法学质量评价评分为5 ~ 8分。选择随机效应模型来组合效应大小。meta分析显示，与对照组相比，VR训练后PD的平衡能力明显改善(标准化平均差[SMD] 2.127, 95% CI 1.202 ~ 3.052, P<。001, I2=95.1, df=15)。 It is worth noting that the intervention platform may be the main reason for heterogeneity. Meta regression analysis showed that no training program could predict the impact of VR training (P=.57 to .94) on PD balance ability. Subgroup result showed that a single training time of 0 to 20 minutes (SMD 6.446), 4 to 6 times per week (SMD 4.067), training for 3 to 5 weeks (SMD 62.478), training course reached more than 30 times (SMD 4.405), and 201 to 300 minutes per week (SMD 4.059) maybe have more benefit. Conclusions: A systematic review and meta-analysis confirmed that VR balance training is a highly effective means to improve balance performance with large effects in PD. In addition, we preliminarily extracted dose-effect relationships for training volume, informing clinicians and practitioners to design effective VR balance training for balance ability. Further research is needed to reveal optimal dose-response relationships following VR balance training. %M 35230242 %R 10.2196/30882 %U https://games.www.mybigtv.com/2022/1/e30882 %U https://doi.org/10.2196/30882 %U http://www.ncbi.nlm.nih.gov/pubmed/35230242