黄天杰，王和银，张一晨，张兰芝，吴沁秀，何晓娟，恒生PY - 2022 DA - 2022/11/10 TI -中国成都变应性鼻炎患者心理障碍的探索性研究JO - JMIR Form Res SP - e37101 VL - 6 IS - 11kw -心理障碍KW -变应性鼻炎KW -成都KW -中国AB -背景:变应性鼻炎(allergic rhinitis, AR)由于疗效不稳定，容易产生精神和心理障碍，全球患者数量已超过5亿。然而，现有的相关文献大多是针对AR合并烦躁、抑郁、焦虑等心理障碍的一对一回顾性分析或有针对性的meta分析，“多医院+跨学科”的多元回归分析较少。目的:本研究旨在通过10种分类方法，准确识别近5年在成都5家最知名医院诊治的AR患者的心理障碍，从而引起耳鼻喉科医师的关注和护理。方法:采用症状自评量表(SCL-90)对827例严格筛选的AR患者按9个分类标准进行心理状态分组和评分。然后在组内比较分数。将研究组与中国常模进行组间比较，提取心理障碍的积极因素。研究组的四种症状，即鼻痒、打喷嚏、明显分泌物和鼻塞，在视觉模拟量表上进行评分。采用多元回归统计方法对提取的心理障碍阳性因素与症状评分进行偏相关分析。结果:827例患者中，无精神健康损害124例(15%)，轻度损害176例(21.3%)，轻至中度损害474例(57.3%)，中度至重度损害41例(5%)，重度损害12例(1.4%)。 The average score of the SCL-90 for all 827 patients was 2.64 (SD 0.25), which corresponded to mild to moderate mental health impairments. The 827 patients scored significantly higher for the 4 positive factors: depression, anxiety, psychosis, and other (sleep, diet). Depression was positively correlated with sneezing and clear discharge, anxiety was positively correlated with nasal itching and congestion, psychosis was positively correlated with nasal itching and sneezing, and other (sleep, diet) was positively correlated with clear discharge and nasal congestion. Conclusions: Patients with AR have mild to moderate mental health impairments, with women and those with abnormal BMI, aged ≥45 years, with a monthly salary <¥5110 (US $700), with a disease duration <13 years, residing in urban areas, with a high school or above education, or who are indoor laborers being at high risk and requiring more care, follow-up, and comprehensive therapy from otolaryngologists. SN - 2561-326X UR - https://formative.www.mybigtv.com/2022/11/e37101 UR - https://doi.org/10.2196/37101 UR - http://www.ncbi.nlm.nih.gov/pubmed/36355407 DO - 10.2196/37101 ID - info:doi/10.2196/37101 ER -