@文章{info:doi/10.2196/36656，作者=“Woodward, Sean F和Bari, Sumra和Vike, Nicole和Lalvani, Shamal和Stetsiv, Khrystyna和Kim, Byoung Woo和Stefanopoulos, Leandros和Maglaveras, Nicos和Breiter, Hans和Katsaggelos, Aggelos K”，标题=“焦虑，COVID-19综合征相关抑郁，以及COVID-19幸存者的自杀想法和行为:横断面研究"，期刊="JMIR Form Res"，年="2022"，月="10"，日="25"，卷="6"，数="10"，页="e36656"，关键词="COVID-19;职位——COVID-19综合症;自杀倾向;抑郁症;患者健康问卷-9;phq - 9;状态特质焦虑指数;背景:尽管COVID-19对一般人群心理健康的影响已经得到了很好的研究，但关于COVID-19对感染者的长期影响的研究相对较新。迄今为止，在COVID-19康复后的几个月里，观察到与COVID-19后综合征(PCS)相关的抑郁、焦虑和神经系统症状。 Suicidal thoughts and behavior (STB) have also been preliminarily proposed as sequelae of COVID-19. Objective: We asked 3 questions. First, do participants reporting a history of COVID-19 diagnosis or a close relative having severe COVID-19 symptoms score higher on depression (Patient Health Questionnaire-9 [PHQ-9]) or state anxiety (State Trait Anxiety Index) screens than those who do not? Second, do participants reporting a COVID-19 diagnosis score higher on PCS-related PHQ-9 items? Third, do participants reporting a COVID-19 diagnosis or a close relative having severe COVID-19 symptoms score higher in STB before, during, or after the first year of the pandemic? Methods: This preliminary study analyzed responses to a COVID-19 and mental health questionnaire obtained from a US population sample, whose data were collected between February 2021 and March 2021. We used the Mann-Whitney U test to detect differences in the medians of the total PHQ-9 scores, PHQ-9 component scores, and several STB scores between participants claiming a past clinician diagnosis of COVID-19 and those denying one, as well as between participants claiming severe COVID-19 symptoms in a close relative and those denying them. Where significant differences existed, we created linear regression models to predict the scores based on COVID-19 response as well as demographics to identify potential confounding factors in the Mann-Whitney relationships. Moreover, for STB scores, which corresponded to 5 questions asking about 3 different time intervals (i.e., past 1 year or more, past 1 month to 1 year, and past 1 month), we developed repeated-measures ANOVAs to determine whether scores tended to vary over time. Results: We found greater total depression (PHQ-9) and state anxiety (State Trait Anxiety Index) scores in those with COVID-19 history than those without (Bonferroni P=.001 and Bonferroni P=.004) despite a similar history of diagnosed depression and anxiety. Greater scores were noted for a subset of depression symptoms (PHQ-9 items) that overlapped with the symptoms of PCS (all Bonferroni Ps<.05). Moreover, we found greater overall STB scores in those with COVID-19 history, equally in time windows preceding, during, and proceeding infection (all Bonferroni Ps<.05). Conclusions: We confirm previous studies linking depression and anxiety diagnoses to COVID-19 recovery. Moreover, our findings suggest that depression diagnoses associated with COVID-19 history relate to PCS symptoms, and that STB associated with COVID-19 in some cases precede infection. ", issn="2561-326X", doi="10.2196/36656", url="https://formative.www.mybigtv.com/2022/10/e36656", url="https://doi.org/10.2196/36656", url="http://www.ncbi.nlm.nih.gov/pubmed/35763757" }