@文章{信息:doi/10.2196/34055，作者=“Coffin, Tara和Bowen, Deborah和Swisher, Elizabeth和Lu, Karen和Rayes, Nadine和Norquist, Barbara和Blank, Stephanie和Levine, Douglas和Bakkum-Gamez, Jamie和Fleming, Gini和Olopade, Olufunmilayo和D'Andrea, Alan和Nebgen, Denise和Peterson, Christine和Munsell, Mark和Gavin, Kathleen和Lechner, Rebecca和Crase, Jamie和Polinsky, Deborah和Romero, Iris”，标题=“基于人群基因检测的无障碍通信系统:开发与可用性研究”，期刊=“JMIR Form Res”，年=“2022”，月=“10”，日=“17”，卷=“6”，数=“10”，页=“e34055”，关键词=“基因检测;互联网;社交媒体;背景:尽管某些与癌症相关的易感基因的致病性变异与卵巢癌风险之间已经建立了良好的联系，但基因检测的使用率很低。考虑到大多数大型保险公司都为那些有遗传性癌症家族史的人提供基因检测，问题可能在于获得基因检测的途径。远程可访问的基于网络的通信系统可以提高对基因检测服务的认识和吸收。目的:本研究旨在介绍支持基因检测实施和获取所需的多步骤基于web的通信系统的开发和形成性评估。方法:在设计多步基于网络的交流系统时，我们考虑了基因检测的各种障碍和促进因素，以可及性维度为指导。除了进行可用性测试之外，我们还对基于web的系统的功能和参与者的反应率进行了持续的评估，目标是继续对基于web的通信系统进行修改，因为它正在使用中。 Results: The combined approach of usability testing and expert user experience consultation resulted in several modifications to the multistep web-based communication system, including changes that related to imagery and content, web accessibility, and general organization of the web-based system. All recommendations were made with the goal of improving the overall accessibility of the web-based communication system. Conclusions: A multistep web-based communication system appears to be an effective way to address many potential barriers to access, which may otherwise make genetic testing difficult for at-risk individuals to participate in. Importantly, some dimensions of access were easy to assess before study recruitment, but other aspects of the communication system required ongoing assessment during the implementation process of the Making Genetic Testing Accessible study. ", issn="2561-326X", doi="10.2196/34055", url="https://formative.www.mybigtv.com/2022/10/e34055", url="https://doi.org/10.2196/34055", url="http://www.ncbi.nlm.nih.gov/pubmed/36251350" }