杂志文章@ 2562-0959 %I JMIR出版物V 5% N 3%卡塔尔世界杯8强波胆分析 T参与退伍军人事务医院附属学术皮肤科医生的临床试验:调查研究西弗辛德,托伦·德安吉洛,约瑟芬·哈佐娃,塔季亚娜·哈桑,沙赫扎布·卡玛拉,迈克尔·华莱士,伊丽莎白·邓尼克,科里·德拉瓦勒,罗伯特+皮肤病服务,落基山地区退伍军人事务医疗中心,美国退伍军人事务部,科罗拉多州东部医疗保健系统,1700 N惠灵街,E1-342室,奥罗拉,美国,1 7208575562,robert.dellavalle@cuanschutz.edu %K皮肤科%K皮肤科医生%K临床试验%K COVID-19 %K基底细胞癌%K银屑病,特应性皮炎%K退伍军人事务%K癌%K癌症治疗%K皮肤科医生%K大流行%D 2022 %7 12.9.2022 %9原始论文%J JMIR Dermatol %G英文%X背景:临床试验导致了许多皮肤病的新有效疗法的发展。据我们所知,目前还没有发表的研究量化和描述了学术皮肤科医生及其大学附属机构参与临床试验的程度。目的:本研究的目的是描述学术皮肤科参与临床试验研究的特征。方法:一项在线调查发送给211退伍军人事务(VA)雇用的皮肤科医生。它包括20个问题,涉及临床试验的数量、致力于临床研究的支持人员、研究的皮肤病以及COVID-19大流行对进行临床研究的影响。在三个月的时间内(2021年3月至5月)发出了三轮调查邀请。对所有调查回复的数据进行了回顾,以对主要结局指标进行定量和描述性分析。结果:共有48名皮肤科医生完成了调查,并提供了他们的大学附属机构和参与临床试验研究的详细信息。 Over half of participants (n=25, 58.1%) with a university affiliate reported that their affiliated dermatology department had a dedicated clinical trials unit. Basal cell carcinoma was the most frequently studied skin condition (n=9, 18.8%), followed by atopic dermatitis and psoriasis (n=4, 8.3% each); 66.7% of participants reported no current clinical trials participation. Of those conducting clinical trials, 87% (n=18) noted that COVID-19 was a barrier to conducting trials, with 52.2% (n=11) citing disrupted or decreased trials due to the pandemic. Conclusions: Although many dermatologists with university affiliations reported having a dedicated clinical trials unit at their institution, a majority of those surveyed reported not taking part in any active trials. Overall, the diseases investigated in academic clinical trials appear to follow national trends, though some of the top dermatological diseases are underrepresented in clinical trials research. A key limitation of our study was the low response rate (~23%) and that the survey responses from the sample of VA-based dermatologists may not be generalizable to all academic dermatology departments in the United States. The effect of the COVID-19 pandemic appeared to play a significant role in disrupting active trials. %M 36187494 %R 10.2196/35379 %U https://derma.www.mybigtv.com/2022/3/e35379 %U https://doi.org/10.2196/35379 %U http://www.ncbi.nlm.nih.gov/pubmed/36187494
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