TY - JOUR AU - Baril, Jonathan-F AU - Bromberg, Simon AU - Moayedi, Yasbanoo AU - Taati, Babak AU - Manlhiot, Cedric AU - Ross, Heather Joan AU - Cafazzo, Joseph PY - 2019 DA - 2019/05/17 TI -使用自由生活步数监测心力衰竭功能分类:验证研究JO - JMIR Cardio SP - e12122 VL - 3 IS - 1 KW -运动生理学KW -心率跟踪器KW -腕戴设备KW - Fitbit KW -心力衰竭KW -步数KW -心肺运动试验KW -动态监测AB -背景:纽约心脏协会(NYHA)功能分类系统评分者间重复性较差。先前发表的一项试点研究显示，通过腕式活动监测器测量，被归类为NYHA功能II类和III类的心力衰竭(射血分数降低)患者的每日步数有统计学上的显著差异。然而，该研究的小样本量严重限制了这一发现在更大范围心力衰竭(HF)人群中推广的科学信心。目的:本研究旨在验证在更大样本的HF伴射血分数降低(HFrEF)患者中进行的初步研究，并试图表征步长计数分布，以获得一种更客观的评估NYHA功能分级的方法。方法:我们对独立记录的50例HFrEF患者(35例NYHA II患者和15例NYHA III患者)的数据集重复了试点研究期间进行的分析。在自由生活的环境中，研究人员用Fitbit Flex监测参与者的步数，为期两周。结果:比较各组中位数，表现为NYHA III类症状的患者记录的2周平均每日总步数显著降低(3541 vs 5729[步]，P=.04)，记录的2周最大每日总步数显著降低(10792 vs 5904[步]，P=.03)，记录的2周平均每日平均步数显著降低(4.0 vs 2.5[步/分钟]，P=.04)，以及记录的2周平均每日每分钟步数最大值显著降低(88.1 vs 96.1和111.0 vs 123.0[步/分钟];P =。分别为02和。004)。 Conclusions: Patients with NYHA II and III symptoms differed significantly by various aggregate measures of free-living step count including the (1) mean and (2) maximum daily total step count as well as by the (3) mean of daily mean step count and by the (4) mean and (5) maximum of the daily per minute step count maximum. These findings affirm that the degree of exercise intolerance of NYHA II and III patients as a group is quantifiable in a replicable manner. This is a novel and promising finding that suggests the existence of a possible, completely objective measure of assessing HF functional class, something which would be a great boon in the continuing quest to improve patient outcomes for this burdensome and costly disease. SN - 2561-1011 UR - http://cardio.www.mybigtv.com/2019/1/e12122/ UR - https://doi.org/10.2196/12122 UR - http://www.ncbi.nlm.nih.gov/pubmed/31758777 DO - 10.2196/12122 ID - info:doi/10.2196/12122 ER -