TY - JOUR AU - Neil, Jordan M AU - Senecal, Christian AU - Ballini, Lauren AU - Chang, Yuchiao AU - Goshe, Brett AU - Flores, Efren AU - Ostroff, Jamie S AU - Park, Elyse R PY - 2022 DA - 2022/8/24 TI -近期诊断为癌症的当前吸烟者的烟草治疗试验招募信息的多方法评估:试验阶乘随机对照试验JO - JMIR癌症SP - e37526 VL - 8 IS - 3kw -可教矩KW -癌症KW -烟草治疗试验KW -吸烟KW -信息框架KW -招募AB -背景:癌症诊断可以催化戒烟动机。烟草治疗试验提供了戒烟资源，但应计率较低。数字推广可能会提高收益，但如何最好地招募最近被诊断为吸烟者的知识有限。目的:本研究旨在确定最有效的信息框架，以促进与医生交谈的意愿，参与最近诊断为癌症的吸烟者的烟草治疗试验。方法:从2019年2月至4月，从一个国家网络小组招募了过去24个月内诊断出的当前吸烟者，进行了一项多方法试点随机试验(N=99)。参与者被随机分配到2×3 +对照因子设计中，该设计测试了3个独特的信息框架:吸烟的近端威胁与远端威胁，继续吸烟的成本与戒烟的好处，以及参与烟草治疗试验的收益与不参与烟草治疗试验的损失。主要结果是有意与医生讨论参与烟草治疗试验。在第1阶段，使用方差分析检查每个信息因子水平内的主要影响，并与对照条件进行比较。收集了其他信息评估和有效性措施，并在多变量模型中预测与医生交谈的意图。 In phase 2, open-text evaluations of the messages were analyzed using natural language processing software (Leximancer) to generate a thematic concept map and Linguistic Inquiry Word Count to identify and compare the prevalence of linguistic markers among message factors. Results: Of the 99 participants, 76 (77%) completed the intervention. Participants who received the cost of continued smoking frame were significantly more likely to intend to talk to their physician about participating in a tobacco treatment trial than those who received the benefits of the quitting frame (mean costs 5.13, SD 1.70 vs mean benefits 4.23, SD 1.86; P=.04). Participants who received the proximal risks of continued smoking frame were significantly more likely to seek more information about participating (mean distal 4.83, SD 1.61 vs mean proximal 5.55, SD 1.15; P=.04), and those who received the losses of not participating frame reported significantly improved perceptions of smoking cessation research (mean gain 3.98, SD 0.83 vs mean loss 4.38, SD 0.78; P=.01). Male participants (P=.006) and those with greater message relevancy (P=.001) were significantly more likely to intend to talk to their physician. Participants’ perceptions of their smoking habits, as well as their motivation to quit smoking, were prevalent themes in the open-text data. Differences in the percentages of affective words across message frames were identified. Conclusions: Multimethod approaches are needed to develop evidence-based recruitment messages for patients recently diagnosed with cancer. Future tobacco treatment trials should evaluate the effectiveness of different message frames on smoker enrollment rates. Trial Registration: Clinicaltrials.gov NCT05471284; https://clinicaltrials.gov/ct2/show/NCT05471284 SN - 2369-1999 UR - https://cancer.www.mybigtv.com/2022/3/e37526 UR - https://doi.org/10.2196/37526 UR - http://www.ncbi.nlm.nih.gov/pubmed/36001378 DO - 10.2196/37526 ID - info:doi/10.2196/37526 ER -