TY - JOUR AU - Dang, Thu Ha AU - Forkan, Abdur Rahim Mohammad AU - Wickramasinghe, Nilmini AU - Jayaraman, Prem Prakash AU - Alexander, Marliese AU - Burbury, Kate AU - Schofield, Penelope PY - 2022 DA - 2022/4/27 TI -加强成人口服抗癌药物依从性的干预方案调查:综述JO - JMIR Cancer SP - e34833 VL - 8 IS - 2 KW -数字KW -干预KW -药物依从性KW -肿瘤学KW -口服抗癌KW -系统评价AB -背景:坚持抗癌药物对癌症治疗的成功至关重要;然而，不坚持服药仍然具有挑战性，而且有有限的证据表明，干预措施可以改善癌症患者对药物的坚持。目的:本综述旨在识别和总结现有的干预措施，以提高成年癌症幸存者对口服抗癌药物的依从性。方法:2名审稿人对7个电子数据库进行了全面检索，他们独立进行了研究选择、使用A Measurement Tool to evaluate Systematic Reviews 2进行质量评估和数据提取。采用PRISMA(系统评价和元分析首选报告项目)2020检查表来报告结果。结果:共有29篇评论被纳入叙事综合。系统评价的总体质量较低。促进依从的4个主要策略集中在教育、提醒、行为和监测以及多成分方法。大多数综述报告了基于数字技术的干预措施(27/ 29,93%)。 A few interventions applied theories (10/29, 34%), design frameworks (2/29, 7%), or engaged stakeholders (1/29, 3%) in the development processes. The effectiveness of interventions was inconsistent between and within reviews. However, interventions using multiple strategies to promote adherence were more likely to be effective than single-strategy interventions (12/29, 41% reviews). Unidirectional communication (7/29, 24% reviews) and technology alone (11/29, 38% reviews) were not sufficient to demonstrate improvement in adherence outcomes. Nurses and pharmacists played a critical role in promoting patient adherence to oral cancer therapies, especially with the support of digital technologies (7/29, 24% reviews). Conclusions: Multicomponent interventions are potentially effective in promoting patient adherence to oral anticancer medicines. The seamless integration of digital solutions with direct clinical contacts is likely to be effective in promoting adherence. Future research for developing comprehensive digital adherence interventions should be evidence-based, theory-based, and rigorously evaluated. SN - 2369-1999 UR - https://cancer.www.mybigtv.com/2022/2/e34833 UR - https://doi.org/10.2196/34833 UR - http://www.ncbi.nlm.nih.gov/pubmed/35475978 DO - 10.2196/34833 ID - info:doi/10.2196/34833 ER -