%0期刊文章%@ 1438- 8871% I JMIR出版物%V 23卡塔尔世界杯8强波胆分析% N 8% P e30715% T探索专业人士和外行人对COVID-19疫苗的表达差异:文本挖掘方法罗A，陈a吉，唐开元，杜玉龙，中国传媒大学传播研究所，北京朝阳区定福庄东街1号，100024,86 13217810927，longbao0927@163.com %K COVID-19 %K疫苗%K知乎%K结构主题建模%K医疗专业人员%K外行%K不良反应%K疫苗接种%K疫苗有效性%K疫苗开发%D 2021 %7 27.8.2021 %9原创论文%J J医学互联网Res %G英文%X背景:COVID-19仍在全球范围内猖獗。到目前为止，COVID-19疫苗是遏制传染和实现群体免疫的最有希望的措施。然而，公众接种疫苗的意愿并不理想。医疗专业人员和门外汉之间有明确的界限。虽然大多数专业人士积极推动疫苗接种运动，但一些非专业人士对COVID-19疫苗表现出怀疑、犹豫甚至反对。目的:本研究旨在采用文本挖掘方法，研究COVID-19疫苗背景下专业人员和非专业人员之间的表达差异和主题差异。方法:我们从中国问答论坛知乎收集了关于COVID-19疫苗的65个过滤问题下的3196个答案。根据问题的内容和描述，将问题分为5类:不良反应、疫苗接种、疫苗有效性、疫苗的社会影响和疫苗开发。 Respondents were also manually coded into two groups: professional and laypeople. Automated text analysis was performed to calculate fundamental expression characteristics of the 2 groups, including answer length, attitude distribution, and high-frequency words. Furthermore, structural topic modeling (STM), as a cutting-edge branch in the topic modeling family, was used to extract topics under each question category, and thematic disparities were evaluated between the 2 groups. Results: Laypeople are more prevailing in the COVID-19 vaccine–related discussion. Regarding differences in expression characteristics, the professionals posted longer answers and showed a conservative stance toward vaccine effectiveness than did laypeople. Laypeople mentioned countries more frequently, while professionals were inclined to raise medical jargon. STM discloses prominent topics under each question category. Statistical analysis revealed that laypeople preferred the “safety of Chinese-made vaccine” topic and other vaccine-related issues in other countries. However, the professionals paid more attention to medical principles and professional standards underlying the COVID-19 vaccine. With respect to topics associated with the social implications of vaccines, the 2 groups showed no significant difference. Conclusions: Our findings indicate that laypeople and professionals share some common grounds but also hold divergent focuses toward the COVID-19 vaccine issue. These incongruities can be summarized as “qualitatively different” in perspective rather than “quantitatively different” in scientific knowledge. Among those questions closely associated with medical expertise, the “qualitatively different” characteristic is quite conspicuous. This study boosts the current understanding of how the public perceives the COVID-19 vaccine, in a more nuanced way. Web-based question and answer forums are a bonanza for examining perception discrepancies among various identities. STM further exhibits unique strengths over the traditional topic modeling method in statistically testing the topic preference of diverse groups. Public health practitioners should be keenly aware of the cognitive differences between professionals and laypeople, and pay special attention to the topics with significant inconsistency across groups to build consensus and promote vaccination effectively. %M 34346885 %R 10.2196/30715 %U //www.mybigtv.com/2021/8/e30715 %U https://doi.org/10.2196/30715 %U http://www.ncbi.nlm.nih.gov/pubmed/34346885