@文章{信息:doi/10.2196/25821，作者=“郑，琪诗和施，鲁明和朱，丽霞和娇，娜娜和Chong，雅生和陈，莎莉惠芝和陈，Yiong Huak和罗，楠和王，文儒和何红姑”，标题=“基于网络和家庭的产后心理教育干预的成本效益:随机对照试验经济评价”，期刊=“J Med Internet Res”，年=“2022”，月=“3”，日=“11”，量=“24”，数=“3”，页数=“e25821”，关键词=“焦虑;成本效益;抑郁症;第一次妈妈;以家庭为基础的;产后;心理教育;自我效能感;社会支持; web-based", abstract="Background: The cost-effectiveness of interventions has attracted increasing interest among researchers. Although web-based and home-based psychoeducational interventions have been developed to improve first-time mothers' postnatal health outcomes, very limited studies have reported their cost-effectiveness. Objective: The aim of this study was to evaluate the cost-effectiveness of web-based and home-based postnatal psychoeducational interventions for first-time mothers during the early postpartum period. Methods: A randomized controlled 3-group pretest and posttest design was adopted, and cost-effectiveness analysis from the health care's perspective was conducted. A total of 204 primiparas were recruited from a public tertiary hospital in Singapore from October 2016 to August 2017 who were randomly allocated to the web-based intervention (n=68), home-based intervention (n=68), or control (n=68) groups. Outcomes of maternal parental self-efficacy, social support, postnatal depression, anxiety, and health care resource utilization were measured using valid and reliable instruments at baseline and at 1 month, 3 months, and 6 months after childbirth. The generalized linear regression models on effectiveness and cost were used to assess the incremental cost-effectiveness ratios of the web-based and home-based intervention programs compared to routine care. Projections of cumulative cost over 5 years incurred by the 3 programs at various coverage levels (ie, 10{\%}, 50{\%}, and 100{\%}) were also estimated. Results: The web-based intervention program dominated the other 2 programs (home-based program and routine care) with the least cost (adjusted costs of SGD 376.50, SGD 457.60, and SGD 417.90 for web-based, home-based, and control group, respectively; SGD 1=USD 0.75) and the best improvements in self-efficacy, social support, and psychological well-being. When considering the implementation of study programs over the next 5 years by multiplying the average cost per first-time mother by the estimated average number of first-time mothers in Singapore during the 5-year projection period, the web-based program was the least costly program at all 3 coverage levels. Based on the 100{\%} coverage, the reduced total cost reached nearly SGD 7.1 million and SGD 11.3 million when compared to control and home-based programs at the end of the fifth year, respectively. Conclusions: The web-based approach was promisingly cost-effective to deliver the postnatal psychoeducational intervention to first-time mothers and could be adopted by hospitals as postnatal care support. Trial Registration: ISRCTN registry ISRCTN45202278; https://www.isrctn.com/ISRCTN45202278 ", issn="1438-8871", doi="10.2196/25821", url="//www.mybigtv.com/2022/3/e25821", url="https://doi.org/10.2196/25821", url="http://www.ncbi.nlm.nih.gov/pubmed/35275078" }