TY - JOUR AU - Neve, Melinda AU - Morgan, Philip J AU - Collins, Clare E PY - 2011 DA - 2011/10/12 TI -商业基于web的减肥计划中的体重变化及其与网站使用的关联:队列研究JO - J Med Internet Res SP - e83 VL - 13 IS - 4kw -减肥KW -肥胖KW -干预KW -互联网KW -商业AB -背景:科学文献中缺乏关于商业减肥计划有效性的信息，包括基于网络的计划。基于网络的减肥计划的潜力已经得到承认，但它们实现显著减肥的能力尚未得到证实。目的:目的是评估参加基于网络的商业减肥计划12周或52周的大型人群的体重变化，并描述参与者使用该计划与体重变化的关系。方法:从2007年8月15日到2008年5月31日，参与者参加了澳大利亚一个基于网络的商业减肥计划。使用自我报告的每周体重记录来确定12周和52周后的体重变化。初步分析使用广义线性混合模型(glmm)对所有订阅了12周的参与者和订阅了52周的参与者进行了体重变化估计。采用最后观测结转(LOCF)方法进行敏感性分析。网站使用情况(即参与者从项目注册到第12周和52周期间登录网站、在网络日记中记录食物或锻炼的天数，或在论坛上发帖的天数)，使用Kruskal-Wallis检验人群平等，以百分比体重变化类别来检验网站使用情况的差异。结果:参与者(n = 9599)的平均(标准差[SD])年龄为35.7(9.5)岁，主要为女性(86%或8279/9599)和肥胖(61%或5866/9599)。 Results from the primary GLMM analysis including all enrollees found the mean percentage weight change was −6.2% among 12-week subscribers (n = 6943) and −6.9% among 52-week subscribers (n = 2656). Sensitivity analysis using LOCF revealed an average weight change of −3.0% and −3.5% after 12 and 52 weeks respectively. The use of all website features increased significantly (P < .01) as percentage weight change improved. Conclusions: The weight loss achieved by 12- and 52-week subscribers of a commercial Web-based weight loss program is likely to be in the range of the primary and sensitivity analysis results. While this suggests that, on average, clinically important weight loss may be achieved, further research is required to evaluate the efficacy of this commercial Web-based weight loss program prospectively using objective measures. The potential association between greater website use and increased weight loss also requires further evaluation, as strategies to improve participants’ use of Web-based program features may be required. SN - 1438-8871 UR - //www.mybigtv.com/2011/4/e83/ UR - https://doi.org/10.2196/jmir.1756 UR - http://www.ncbi.nlm.nih.gov/pubmed/21993231 DO - 10.2196/jmir.1756 ID - info:doi/10.2196/jmir.1756 ER -