@文章{info:doi/10.2196/37480，作者="Garcia, Laura和Birckhead, Brandon和Krishnamurthy, Parthasarathy和Mackey, Ian和Sackman, Josh和Salmasi, Vafi和Louis, Robert和Castro, Carina和Maddox, Roselani和Maddox, Todd和Darnall, Beth D"，标题=" 8周自我管理的基于家庭的虚拟现实项目治疗慢性腰痛的效果持久性:一项随机临床试验随访研究”，期刊=《J Med Internet Res》，年=“2022”，月=“5”，日=“25”，卷=“24”，数=“5”，页=“e37480”，关键词=“行为健康;慢性腰痛;治疗;背景:我们之前报道了一项为期8周的基于家庭的沉浸式虚拟现实(VR)治疗项目的疗效，该项目是一项双盲随机安慰剂对照研究。以社区为基础、自我报告慢性腰痛的成年人被随机1:1接受(1)56天沉浸式治疗性疼痛缓解技能VR项目(EaseVRx)或(2)56天假VR项目。治疗后即刻结果显示治疗性VR在减轻疼痛强度方面优于假性VR;与活动、情绪和压力相关的疼痛干扰(但不包括睡眠);生理功能;和睡眠障碍。 At 3 months posttreatment, therapeutic VR maintained superiority for reducing pain intensity and pain-related interference with activity, stress, and sleep (new finding). Objective: This study assessed between-group and within-group treatment effects 6 months posttreatment to determine the extended efficacy, magnitude of efficacy, and clinical importance of home-based therapeutic VR. Methods: E-surveys were deployed at pretreatment, end-of-treatment, and posttreatment months 1, 2, 3, and 6. Self-reported data for 188 participants were analyzed in a mixed-model framework using a marginal model to allow for correlated responses across the repeated measures. Primary outcomes were pain intensity and pain-related interference with activity, mood, stress, and sleep at 6 months posttreatment. Secondary outcomes were Patient-Reported Outcome Measurement Information System (PROMIS) sleep disturbance and physical function. Results: Therapeutic VR maintained significant and clinically meaningful effects 6 months posttreatment and remained superior to sham VR for reducing pain intensity and pain-related interference with activity, stress, and sleep (ds=0.44-0.54; P<.003). Between-group comparisons for physical function and sleep disturbance showed superiority of EaseVRx over sham VR (ds=0.34; P=.02 and ds=0.46; P<.001, respectively). Participants were encouraged to contact study staff with any problems experienced during treatment; however, no participants contacted study staff to report adverse events of any type, including nausea and motion sickness. Conclusions: Our 8-week home-based VR pain management program caused important reductions in pain intensity and interference up to 6 months after treatment. Additional studies are needed in diverse samples. Trial Registration: ClinicalTrials.gov NCT04415177; https://clinicaltrials.gov/ct2/show/NCT04415177 International Registered Report Identifier (IRRID): RR2-10.2196/25291 ", issn="1438-8871", doi="10.2196/37480", url="//www.mybigtv.com/2022/5/e37480", url="https://doi.org/10.2196/37480", url="http://www.ncbi.nlm.nih.gov/pubmed/35612905" }