@Article{info:doi/10.2196/15199，作者=“Pfaff, Emily Rose和Champion, James和Bradford, Robert Louis和Clark, Marshall和Xu, Hao和Fecho, Karamarie和Krishnamurthy, Ashok和Cox, Steven和Chute, Christopher G和Overby Taylor, Casey和Ahalt, Stan”，标题=“快速医疗互操作性资源(FHIR)作为集成通用数据模型的元模型:《工具开发与定量验证研究》，期刊=“JMIR Med Inform”，年=“2019”，月=“Oct”，日=“16”，卷=“7”，号=“4”，页=“e15199”，关键词=“卫生信息互操作性;电子健康记录;数据共享;背景:在多站点临床研究合作中，机构可能使用也可能不使用相同的公共数据模型(CDM)来存储临床数据。为了克服这一挑战，我们建议使用Health Level 7的快速医疗互操作性资源(FHIR)作为元cdm——表示临床数据的单一标准。目的:在本研究中，我们旨在创建一个开源应用程序，称为临床资产映射程序为FHIR (CAMP FHIR)，以有效地将临床数据转换为FHIR，以支持来源无关的cdm -FHIR映射。方法:CAMP FHIR映射包括(1)将每个源变量映射到其对应的FHIR元素，(2)将源数据值集中的每个项映射到具有严格值集的变量对应的FHIR值集项。迄今为止，CAMP FHIR已用于将108个变量从生物学信息学集成、床边(i2b2)和以患者为中心的结果研究网络数据模型转换为跨7个FHIR资源的领域。它的设计允许从任何源数据模型输入，并将在未来支持额外的FHIR资源。 Results: We have used CAMP FHIR to transform data on approximately 23,000 patients with asthma from our institution's i2b2 database. Data quality and integrity were validated against the origin point of the data, our enterprise clinical data warehouse. Conclusions: We believe that CAMP FHIR can serve as an alternative to implementing new CDMs on a project-by-project basis. Moreover, the use of FHIR as a CDM could support rare data sharing opportunities, such as collaborations between academic medical centers and community hospitals. We anticipate adoption and use of CAMP FHIR to foster sharing of clinical data across institutions for downstream applications in translational research. ", issn="2291-9694", doi="10.2196/15199", url="https://medinform.www.mybigtv.com/2019/4/e15199", url="https://doi.org/10.2196/15199", url="http://www.ncbi.nlm.nih.gov/pubmed/31621639" }